| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10025262m |
| Family | GT47 |
| Protein Properties | Length: 450 Molecular Weight: 51075.8 Isoelectric Point: 9.6364 |
| Chromosome | Chromosome/Scaffold: 4 Start: 9720209 End: 9722048 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 61 | 373 | 0 |
| RVRVYMYNLPKRFTYGLIEQHSIARGGIKKPGDDVTTLKYPGHQHMHEWYLFSDLNRPEVDRSGSPIVRVLDPADADLFYVPVFSSLSLIVNAGRPVEPG SGYSDENMQEGLMEWLEGQEWWRRNGGRDHVIPAGDPNALYRILDRVKNAVLLVADFGRLRPDQGSFVKDVVIPYSHRVNLFNGEIGVEARKTLLFFMGN RYRKDGGKVRDLLFQVLEKEEDVTIKHGTQSRENRRAATKGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPVIVSDSIELPFEDVIDYRKFSIFVEANAA LHPGFLVKMLRKI | |||
| Full Sequence |
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| Protein Sequence Length: 450 Download |
| MARKSSLLKR AAIAVVSVIA IYVILNASVS RSLPSSSDLP RQLIREEDDD DQGRRAPIQP 60 RVRVYMYNLP KRFTYGLIEQ HSIARGGIKK PGDDVTTLKY PGHQHMHEWY LFSDLNRPEV 120 DRSGSPIVRV LDPADADLFY VPVFSSLSLI VNAGRPVEPG SGYSDENMQE GLMEWLEGQE 180 WWRRNGGRDH VIPAGDPNAL YRILDRVKNA VLLVADFGRL RPDQGSFVKD VVIPYSHRVN 240 LFNGEIGVEA RKTLLFFMGN RYRKDGGKVR DLLFQVLEKE EDVTIKHGTQ SRENRRAATK 300 GMHTSKFCLN PAGDTPSACR LFDSIVSLCV PVIVSDSIEL PFEDVIDYRK FSIFVEANAA 360 LHPGFLVKML RKIKPKKILE YQREMRSVKR YFDYDNPNGA VKEIWRQVSQ KLPLIKLMSN 420 RDRRLVLRNL TEPNCSCLCT NLTGLITSS* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-82 | 58 | 373 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC61825.1 | 0 | 1 | 387 | 1 | 385 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_199306.1 | 0 | 9 | 446 | 14 | 440 | ARAD2 (ARABINAN DEFICIENT 2); catalytic [Arabidopsis thaliana] |
| RefSeq | NP_850241.1 | 0 | 1 | 448 | 1 | 446 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002322391.1 | 0 | 1 | 448 | 1 | 456 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523645.1 | 0 | 1 | 448 | 1 | 451 | catalytic, putative [Ricinus communis] |
