| Basic Information | |
|---|---|
| Species | Capsella rubella |
| Cazyme ID | Carubv10026133m |
| Family | AA7 |
| Protein Properties | Length: 589 Molecular Weight: 66222 Isoelectric Point: 10.0912 |
| Chromosome | Chromosome/Scaffold: 8 Start: 1698710 End: 1701209 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 132 | 584 | 0 |
| PKPGFIFRPVHESQVQASIICSKKLKIHFRVRSGGHDFEAMSFVSRIERPFILIDFAKLRRVDVDIKNNSTWVQAGATLGELYYRIAEKSKVHGYPAGLC TSVGIGGYMTGGGYGSLMRKYGLAGDNVLDVKMIDANGKLLNRATMGEDLFWALRGGGGASFGIVLAWKIKLVPVPETLTMFTVTKTPKQDPGLEIISKW QRIASKVMEELHIRVEFTAVGNKGNRTVMMSYKGQFLGKKVTLMKVMNKVFPELGLTQEDCTEMSWIEAALVNGGFKNGSTIDVLLQLQSPLGKTYYKAK SDFVKEPIPALGLQGLFERLIQEDIPFVNWTPYGGMMARIPESEIPFPHRNGTLFKILYQINWPANDKRPSRHVNWMRELYSYMAPYVSSNPRQAYVNYR DLDLGQNMNNNAKVNSIEAKIWGAKYFKGNYDRLVKIKTKVDPENFFRNEQSI | |||
| Full Sequence |
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| Protein Sequence Length: 589 Download |
| NTNTSITILK PHYVFGFLSS KVYKHVSSLT LKNQEKTHIH SHLVLATGRE MAISKPLFPI 60 ISCVTFLVLY CVTPTSSSAS LQEQFISCVK SNTHVSLPLD KTIFTPTKNV SMFDQVLEST 120 AQNLRFLAKS MPKPGFIFRP VHESQVQASI ICSKKLKIHF RVRSGGHDFE AMSFVSRIER 180 PFILIDFAKL RRVDVDIKNN STWVQAGATL GELYYRIAEK SKVHGYPAGL CTSVGIGGYM 240 TGGGYGSLMR KYGLAGDNVL DVKMIDANGK LLNRATMGED LFWALRGGGG ASFGIVLAWK 300 IKLVPVPETL TMFTVTKTPK QDPGLEIISK WQRIASKVME ELHIRVEFTA VGNKGNRTVM 360 MSYKGQFLGK KVTLMKVMNK VFPELGLTQE DCTEMSWIEA ALVNGGFKNG STIDVLLQLQ 420 SPLGKTYYKA KSDFVKEPIP ALGLQGLFER LIQEDIPFVN WTPYGGMMAR IPESEIPFPH 480 RNGTLFKILY QINWPANDKR PSRHVNWMRE LYSYMAPYVS SNPRQAYVNY RDLDLGQNMN 540 NNAKVNSIEA KIWGAKYFKG NYDRLVKIKT KVDPENFFRN EQSIPPMM* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR00387 | glcD | 0.005 | 183 | 309 | 136 | + glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity [Energy metabolism, Other]. | ||
| pfam01565 | FAD_binding_4 | 8.0e-19 | 134 | 273 | 141 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| COG0277 | GlcD | 2.0e-19 | 134 | 586 | 471 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam08031 | BBE | 3.0e-20 | 526 | 585 | 60 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAL24314.1 | 0 | 51 | 587 | 1 | 540 | berberine bridge enzyme-like protein [Arabidopsis thaliana] |
| RefSeq | NP_199251.1 | 0 | 51 | 587 | 1 | 539 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_199252.1 | 0 | 51 | 587 | 1 | 540 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_199253.1 | 0 | 51 | 588 | 1 | 537 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | XP_002268361.1 | 0 | 66 | 587 | 9 | 527 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 79 | 587 | 1 | 513 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 73 | 588 | 1 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 73 | 588 | 1 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 107 | 588 | 26 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 107 | 588 | 26 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777438 | 553 | 46 | 585 | 0 |
| HO206811 | 246 | 60 | 305 | 0 |
| EG515109 | 292 | 115 | 405 | 0 |
| EG515098 | 292 | 116 | 407 | 0 |
| EG515110 | 264 | 49 | 311 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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