| Basic Information | |
|---|---|
| Species | Citrus clementina |
| Cazyme ID | Ciclev10001104m |
| Family | GT47 |
| Protein Properties | Length: 456 Molecular Weight: 52304 Isoelectric Point: 9.5547 |
| Chromosome | Chromosome/Scaffold: 5 Start: 38278463 End: 38282008 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 80 | 377 | 0 |
| LSLKIYVYDENELDGLKLLLYGRDGAISADSCVKGQWGTQVKIHRLLLQSRFRTKKKEEADLFFVPAYAKCVRMMGGLNDKEINQTYVKVLRQMPYFRRS GGRDHIFVFPSGAGAHLFKSWATFINRSIILTPEGDRTDKRDTSAFNTWKDIIIPGNVDDGMTKRGLTLVQPLPLSKRKYLANYLGRAQGKVGRLQLIEL ANQYPDQLESPDLKFKGPEKLGKIEYFQHLRNAKFCLAPRGESSWTLRFYESFFVECVPVILSDEAEFPFQNVIDYTQISIKWPSSRIGRQLLDYLAT | |||
| Full Sequence |
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| Protein Sequence Length: 456 Download |
| MGSSHNNKSR IFTPCTRTHQ IGALLLVTTT FFLTRLFDQS FSPCHSSPVN QDGISHRNHV 60 HISDGGRSIS WPERGYGSHL SLKIYVYDEN ELDGLKLLLY GRDGAISADS CVKGQWGTQV 120 KIHRLLLQSR FRTKKKEEAD LFFVPAYAKC VRMMGGLNDK EINQTYVKVL RQMPYFRRSG 180 GRDHIFVFPS GAGAHLFKSW ATFINRSIIL TPEGDRTDKR DTSAFNTWKD IIIPGNVDDG 240 MTKRGLTLVQ PLPLSKRKYL ANYLGRAQGK VGRLQLIELA NQYPDQLESP DLKFKGPEKL 300 GKIEYFQHLR NAKFCLAPRG ESSWTLRFYE SFFVECVPVI LSDEAEFPFQ NVIDYTQISI 360 KWPSSRIGRQ LLDYLATIPD EHIEQMIAHG RQIRCLWAYA PETEPCSAMQ GIMWELQRKV 420 RQFHLSAETF WLHNGSIVNR DLVEFNNWKL PVRLP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-42 | 82 | 360 | 292 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564141.1 | 0 | 1 | 455 | 1 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 1 | 455 | 1 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 1 | 455 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 1 | 455 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 1 | 455 | 1 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX668832 | 291 | 142 | 432 | 0 |
| DY295548 | 342 | 1 | 341 | 0 |
| DY290282 | 280 | 1 | 280 | 0 |
| FC879842 | 274 | 1 | 274 | 0 |
| DY295548 | 56 | 290 | 342 | 0.025 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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