| Basic Information | |
|---|---|
| Species | Citrus clementina |
| Cazyme ID | Ciclev10006541m |
| Family | AA3 |
| Protein Properties | Length: 571 Molecular Weight: 62857.4 Isoelectric Point: 6.5119 |
| Chromosome | Chromosome/Scaffold: 9 Start: 28462026 End: 28466344 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 40 | 566 | 0 |
| SYYDYIIVGGGTSGCPLAATLSQNATVLLLEKGGSPYENPNITDTGNFATTLLDPSPTSPSQQFISEDGVYNARARVLGGGSVINAGFYTRASLRYVREV GWTESLVNSSYEWVEKKVAHEPPMLQWQSAVRDGLLEAGVLPYNGFTFDHIYGTKVSGTIFDEDGHRHSAADLLEYADPEKLTVYLRAVVQRIKFTETGR AKPTAHCVTFYDHVGARHRACLNNGGKNEIILSAGAIGSPQLLMLSGVGPANELRKRGIRVVVDQPNVGQGMSDNPMNALFVPSARPVEVSLVQVVGITR FDSYIETASGLSLAPSWAQGLTRDYSSFLNKTDIPSLVTPETVAEAVETVNSYLNGTIRAGVIVEKIMGPRSTGHLRLRTLDADDNPSVTFNYFQEPEDL VRCVQGMRTIIDVLNSRALSKFRYPDVSVQELIDLMVNIPTNLRPRHVVGASISLEQFCRDTVMTIWHYHGGCQVDRVVDRDYKVLGVDGLRVIDGSTFY NSPGTNPQATCMMLGRYMGLRILQDRD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 571 Download |
| MGLQFWRFAV IIFLFHGFCF AEKAPYYTFV KDATSAPLIS YYDYIIVGGG TSGCPLAATL 60 SQNATVLLLE KGGSPYENPN ITDTGNFATT LLDPSPTSPS QQFISEDGVY NARARVLGGG 120 SVINAGFYTR ASLRYVREVG WTESLVNSSY EWVEKKVAHE PPMLQWQSAV RDGLLEAGVL 180 PYNGFTFDHI YGTKVSGTIF DEDGHRHSAA DLLEYADPEK LTVYLRAVVQ RIKFTETGRA 240 KPTAHCVTFY DHVGARHRAC LNNGGKNEII LSAGAIGSPQ LLMLSGVGPA NELRKRGIRV 300 VVDQPNVGQG MSDNPMNALF VPSARPVEVS LVQVVGITRF DSYIETASGL SLAPSWAQGL 360 TRDYSSFLNK TDIPSLVTPE TVAEAVETVN SYLNGTIRAG VIVEKIMGPR STGHLRLRTL 420 DADDNPSVTF NYFQEPEDLV RCVQGMRTII DVLNSRALSK FRYPDVSVQE LIDLMVNIPT 480 NLRPRHVVGA SISLEQFCRD TVMTIWHYHG GCQVDRVVDR DYKVLGVDGL RVIDGSTFYN 540 SPGTNPQATC MMLGRYMGLR ILQDRDRISF * 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01810 | betA | 5.0e-21 | 43 | 314 | 305 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| pfam05199 | GMC_oxred_C | 5.0e-25 | 409 | 554 | 151 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR03970 | Rv0697 | 7.0e-34 | 43 | 554 | 556 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| COG2303 | BetA | 2.0e-44 | 42 | 570 | 578 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 27 | 565 | 553 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI31862.1 | 0 | 1 | 565 | 1 | 537 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI34759.1 | 0 | 16 | 565 | 21 | 571 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002267807.1 | 0 | 1 | 565 | 1 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002267848.1 | 0 | 1 | 565 | 1 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002510860.1 | 0 | 6 | 565 | 6 | 570 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3red_L | 0 | 26 | 565 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_K | 0 | 26 | 565 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_J | 0 | 26 | 565 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_I | 0 | 26 | 565 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
| PDB | 3red_H | 0 | 26 | 565 | 11 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
