Basic Information | |
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Species | Citrus clementina |
Cazyme ID | Ciclev10010628m |
Family | GT47 |
Protein Properties | Length: 767 Molecular Weight: 88157.9 Isoelectric Point: 9.7687 |
Chromosome | Chromosome/Scaffold: 1 Start: 25871865 End: 25876939 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 429 | 714 | 0 |
KKFKVWIYKEGEHPTVHIGPMHNKYAIEGQFIDEMESKNNPFRASHPDEAHAFFLPVSVANVVQYVYQPITTVKDYSRDRLQRLLTDYVTVVADKYPYWN RSNGADHFMVSCHDWAPEISKYEPELFKNFIRVLCNANNSEGFQPRSDVSMPEIYLPFGRLGPPNMGQTPNYRPIFSFFSGRPNGNIRKLLFNHWKDRDN EVRVYKSLPKGYNYTKMMGQSKFCLCPSGFEVASPREVEAIYAGCVPVVISDNYTLPFSDVLNWSQFSIQIPSQKIPEIKNILKAI |
Full Sequence |
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Protein Sequence Length: 767 Download |
MKDNEYVLHY YRANWPIKEA LFSIFRWHNE TLNVWTHLIG FIIFVALTVA NLMEVPQVAG 60 LVSFFTRSFP NSGDTNVSHG SNGFFTGGGA KNLVDLKQIA SSEMGANIPP ATTPVTRWPF 120 LVFLAGSMFC LLSSSICHLF CCHSRRLNIL LLRIDYSGIT VMIITSFFPP IYYIFQCEPR 180 WHFIYLGGVT ALGIFTIVTL LSPALSAGKF RAFRALLFCS MGFFGFVPAI HAAIVNWNNP 240 KRDITLAYES AMALFYLTGT MVYVTRIPER WKPGWFDLAG HSHQIFHVFV VFGALAHYSA 300 TLVFLEWRDR FGSFLLFLIL LLTFSSPFTE KRVDVASFFS TFETRNVRVA QFFINASSSP 360 PQVSSINKFY KARSIRVEED LAQARAAIRK AIHLQNYTSH SHRTETFIPT GSIYKNAYSF 420 HQSHTEMVKK FKVWIYKEGE HPTVHIGPMH NKYAIEGQFI DEMESKNNPF RASHPDEAHA 480 FFLPVSVANV VQYVYQPITT VKDYSRDRLQ RLLTDYVTVV ADKYPYWNRS NGADHFMVSC 540 HDWAPEISKY EPELFKNFIR VLCNANNSEG FQPRSDVSMP EIYLPFGRLG PPNMGQTPNY 600 RPIFSFFSGR PNGNIRKLLF NHWKDRDNEV RVYKSLPKGY NYTKMMGQSK FCLCPSGFEV 660 ASPREVEAIY AGCVPVVISD NYTLPFSDVL NWSQFSIQIP SQKIPEIKNI LKAIPNEKYL 720 KMYKRVNRVK RHFMLNRPAK PFDVMHMVLH SVWLRRLNFR LATLSQ* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR01065 | hlyIII | 1.0e-7 | 111 | 305 | 208 | + channel protein, hemolysin III family. This family includes proteins from pathogenic and non-pathogenic bacteria, Homo sapiens and Drosophila. In Bacillus cereus, a pathogen, it has been show to function as a channel-forming cytolysin. The human protein is expressed preferentially in mature macrophages, consistent with a role cytolytic role. | ||
COG1272 | COG1272 | 2.0e-27 | 1 | 308 | 312 | + Predicted membrane protein, hemolysin III homolog [General function prediction only] | ||
pfam03006 | HlyIII | 1.0e-45 | 25 | 298 | 275 | + Haemolysin-III related. Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It has been proposed that YOL002c encodes a Saccharomyces cerevisiae protein that plays a key role in metabolic pathways that regulate lipid and phosphate metabolism. In eukaryotes, members are seven-transmembrane pass molecules found to encode functional receptors with a broad range of apparent ligand specificities, including progestin and adipoQ receptors, and hence have been named PAQR proteins. The mammalian members include progesterone binding proteins. Unlike the case with GPCR receptor proteins, the evolutionary ancestry of the members of this family can be traced back to the Archaea. | ||
pfam03016 | Exostosin | 4.0e-59 | 427 | 714 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
GO:0016021 | integral to membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03872.1 | 0 | 376 | 761 | 81 | 465 | Exostosin-like [Medicago truncatula] |
GenBank | ABP03873.1 | 0 | 364 | 761 | 228 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CBI25537.1 | 0 | 318 | 761 | 33 | 475 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 371 | 761 | 4 | 394 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324623.1 | 0 | 427 | 762 | 1 | 336 | predicted protein [Populus trichocarpa] |