Basic Information | |
---|---|
Species | Citrus clementina |
Cazyme ID | Ciclev10010873m |
Family | GT47 |
Protein Properties | Length: 348 Molecular Weight: 40188.4 Isoelectric Point: 9.5755 |
Chromosome | Chromosome/Scaffold: 367 Start: 8791 End: 11187 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 111 | 348 | 0 |
ETLKVYVYKEGQRPILHEPVLKGIYASEGWFMKQLEANKQFVTRDSRKAHLFYLPFSSRMLEETLYVQNSHNHKDLIQYLRNYVNMISAKHNFWNRTEGA DHFLVACHDWAPAETRIIMANCIRALCNSDVKQGFVFGKDVSLPETNVLSPQNPLWAIGGKPASQRSILAFFAGSMHGYLRPILLHHWENKDPDMKIFGQ MPKAKGRGKRKGKMDYIQHMKSSKYCICAKGYEVHSPR |
Full Sequence |
---|
Protein Sequence Length: 348 Download |
MGYEIRSLCQ GETKRLLWPM GIMLTVIVAF QYFELPYDHV LSSVFSTGKV PAPAVENNSL 60 SPRLSSAVDQ EMLYARSQIE NAPLLKNDHE LYAPLYRNVS RFKRSYELME ETLKVYVYKE 120 GQRPILHEPV LKGIYASEGW FMKQLEANKQ FVTRDSRKAH LFYLPFSSRM LEETLYVQNS 180 HNHKDLIQYL RNYVNMISAK HNFWNRTEGA DHFLVACHDW APAETRIIMA NCIRALCNSD 240 VKQGFVFGKD VSLPETNVLS PQNPLWAIGG KPASQRSILA FFAGSMHGYL RPILLHHWEN 300 KDPDMKIFGQ MPKAKGRGKR KGKMDYIQHM KSSKYCICAK GYEVHSPR |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-39 | 113 | 348 | 256 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI20855.1 | 0.000000007 | 1 | 54 | 1 | 54 | unnamed protein product [Vitis vinifera] |
EMBL | CBI20855.1 | 0 | 59 | 348 | 258 | 542 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0.000000008 | 1 | 54 | 1 | 54 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 59 | 348 | 286 | 570 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324801.1 | 0 | 59 | 348 | 14 | 299 | predicted protein [Populus trichocarpa] |