Basic Information | |
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Species | Citrus clementina |
Cazyme ID | Ciclev10014250m |
Family | CBM57 |
Protein Properties | Length: 855 Molecular Weight: 94957.6 Isoelectric Point: 6.0185 |
Chromosome | Chromosome/Scaffold: 2 Start: 31344537 End: 31347747 |
Description | hercules receptor kinase 2 |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CBM57 | 224 | 378 | 3.6e-22 |
YRLNVGGPEIKPSRDPDLWRMWEADSSYMITANAGSEIRNSSNITYASMNDSSVAPLLVYETARTMSNTEVLEKRFNMSWKFEVDPNFDYFVRLHFCELV YEKANQRIFRIYINNRTAENNFDIFMQAGGKNRGYHRDYFDAVSSKIETLWIQLG |
Full Sequence |
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Protein Sequence Length: 855 Download |
MLLMERVLLF LVIMLVVARI GEARSKSFLI NCGTNSSVNV DGRKWVGDLA SNNNVTLSSS 60 GIAATTDSLS GDSIYEPLYR SARVFSDGLN YTFEIIPGNY IVRLHFCPFP LEDYNVNKSS 120 FGVAANGLKL LSEFSAPGEI SHKNLYLQSS GGNSSSISLV KEYFLGIDLD KLMIEFIPSK 180 GSFGFINAIE IVPVVDKLFA DTINKVGGND VNFNLSGRGV ETMYRLNVGG PEIKPSRDPD 240 LWRMWEADSS YMITANAGSE IRNSSNITYA SMNDSSVAPL LVYETARTMS NTEVLEKRFN 300 MSWKFEVDPN FDYFVRLHFC ELVYEKANQR IFRIYINNRT AENNFDIFMQ AGGKNRGYHR 360 DYFDAVSSKI ETLWIQLGPD TAVGAAGTDA LLNGLEIFKL SQNGNLASVE RFDSSGNPVG 420 RSNKWILLVG IGAGIASVVV LAVLFALIFC YCKNRREKSS DPKNNSPGWR PLFFHRGTLN 480 STANAKGSGT RYLNGSVAST RAGKQFTLAE IRAATNNFDE SLMIGVGGFG KVFKGEIEDC 540 TLVAIKRANP QSEQGLAEFE TEIEMLSKLR HRHLVSLIGF CDEQNEMILV YEYMANGTLR 600 SHLFGCDLPP LTWKQRLDAC IGAARGLHYL HTGAERGIIH RDVKTTNILL DENFVAKMSD 660 FGLSKTGPSM EHTHVSTAVK GSFGYLDPEY FWRQQLTEKS DVYSFGVVLF EVVCARAVIN 720 PTLPKDQINL AEWAMKWQKQ RSLKSIIDPH LKGNYSPESL EKFGEIAEKC LDDEGKNRPT 780 MGEVLWHLEY VLQLHEAWMS TNDRQNSFSS SQALGEFAER EAEDRQDAPT PDAENSSGLK 840 MTGEFGSATM GISK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam07714 | Pkinase_Tyr | 7.0e-44 | 539 | 714 | 177 | + Protein tyrosine kinase. | ||
smart00219 | TyrKc | 3.0e-44 | 543 | 788 | 253 | + Tyrosine kinase, catalytic domain. Phosphotransferases. Tyrosine-specific kinase subfamily. | ||
smart00221 | STYKc | 8.0e-45 | 541 | 788 | 255 | + Protein kinase; unclassified specificity. Phosphotransferases. The specificity of this class of kinases can not be predicted. Possible dual-specificity Ser/Thr/Tyr kinase. | ||
cd00192 | PTKc | 4.0e-46 | 541 | 789 | 259 | + Catalytic domain of Protein Tyrosine Kinases. Protein Tyrosine Kinase (PTK) family, catalytic domain. This PTKc family is part of a larger superfamily that includes the catalytic domains of protein serine/threonine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase (PI3K). PTKs catalyze the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates. They can be classified into receptor and non-receptor tyr kinases. PTKs play important roles in many cellular processes including, lymphocyte activation, epithelium growth and maintenance, metabolism control, organogenesis regulation, survival, proliferation, differentiation, migration, adhesion, motility, and morphogenesis. Receptor tyr kinases (RTKs) are integral membrane proteins which contain an extracellular ligand-binding region, a transmembrane segment, and an intracellular tyr kinase domain. RTKs are usually activated through ligand binding, which causes dimerization and autophosphorylation of the intracellular tyr kinase catalytic domain, leading to intracellular signaling. Some RTKs are orphan receptors with no known ligands. Non-receptor (or cytoplasmic) tyr kinases are distributed in different intracellular compartments and are usually multi-domain proteins containing a catalytic tyr kinase domain as well as various regulatory domains such as SH3 and SH2. PTKs are usually autoinhibited and require a mechanism for activation. In many PTKs, the phosphorylation of tyr residues in the activation loop is essential for optimal activity. Aberrant expression of PTKs is associated with many development abnormalities and cancers. | ||
pfam12819 | Malectin_like | 8.0e-60 | 30 | 400 | 383 | + Carbohydrate-binding protein of the ER. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. The domain is found on a number of plant receptor kinases. |
Gene Ontology | |
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GO Term | Description |
GO:0004672 | protein kinase activity |
GO:0006468 | protein phosphorylation |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI31024.1 | 0 | 4 | 853 | 1 | 843 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002264211.1 | 0 | 4 | 853 | 46 | 888 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002299052.1 | 0 | 8 | 836 | 12 | 833 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002330599.1 | 0 | 8 | 829 | 12 | 832 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523186.1 | 0 | 8 | 834 | 12 | 834 | kinase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2qkw_B | 0 | 508 | 797 | 31 | 319 | A Chain A, Structural Basis For Activation Of Plant Immunity By Bacterial Effector Protein Avrpto |
PDB | 3hgk_D | 0 | 508 | 797 | 31 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_C | 0 | 508 | 797 | 31 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_B | 0 | 508 | 797 | 31 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_A | 0 | 508 | 797 | 31 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
Transmembrane Domains | ||||
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Start | End | |||
426 | 448 |
Signal Peptide | ||||
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Cleavage Site | ||||
23 |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
ES805185 | 342 | 448 | 784 | 0 |
GH270923 | 254 | 583 | 836 | 0 |
ES793081 | 252 | 574 | 825 | 0 |
EX357602 | 246 | 539 | 784 | 0 |
JG961928 | 270 | 541 | 810 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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