| Basic Information | |
|---|---|
| Species | Citrus clementina |
| Cazyme ID | Ciclev10019611m |
| Family | AA3 |
| Protein Properties | Length: 543 Molecular Weight: 59125.2 Isoelectric Point: 7.3765 |
| Chromosome | Chromosome/Scaffold: 3 Start: 6736406 End: 6740091 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 40 | 535 | 0 |
| TAAKPVSYYDYIVIGGGTAGCPLAASLSQNASVLLLERGDSPYGNPNITNSGSFSAELADLSPTSPSQRFISEDGVVSTRARVLGGGTCINAGFYTRAEP SFVREEGWDGRLVNESYQWVEKKVVFRPPMQRWQSALRDGLVEVGVLPYNGFTYDHLYGTKIGGTIIDQNNQRHTAADLLEYANPSGLTVLLHASVHKIL FRNKGKARPVAHGVVFRDATGAEHIAYLRNGPMNEIIVSAGALGSPQLLMLSGVGPAEHLKAHNITVVLDQPLVGQGMSDNPMNAIFVPSPVPVEVSLIQ VVGITQFGSYIEGASGVNFAGGSPSPRPYRGGFIFEKIVGPESTGHLELRTRNPNDNPSVTFNYFKEPEDLQRCVQGISTIEKIIESKSFSRFKYDNMSV ETLLNMTASMPLNLLPKHSNASTSLEQFCRDTVMTIWHYHGGCQVGKVVDHDYKVLGVDALRVVDGSTFYYSPGTNPQATVMMLGRYMGVRILRER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 543 Download |
| MDLGCLRLSF VATLATFLFF HDFCACQKAA PNYSFMRNAT AAKPVSYYDY IVIGGGTAGC 60 PLAASLSQNA SVLLLERGDS PYGNPNITNS GSFSAELADL SPTSPSQRFI SEDGVVSTRA 120 RVLGGGTCIN AGFYTRAEPS FVREEGWDGR LVNESYQWVE KKVVFRPPMQ RWQSALRDGL 180 VEVGVLPYNG FTYDHLYGTK IGGTIIDQNN QRHTAADLLE YANPSGLTVL LHASVHKILF 240 RNKGKARPVA HGVVFRDATG AEHIAYLRNG PMNEIIVSAG ALGSPQLLML SGVGPAEHLK 300 AHNITVVLDQ PLVGQGMSDN PMNAIFVPSP VPVEVSLIQV VGITQFGSYI EGASGVNFAG 360 GSPSPRPYRG GFIFEKIVGP ESTGHLELRT RNPNDNPSVT FNYFKEPEDL QRCVQGISTI 420 EKIIESKSFS RFKYDNMSVE TLLNMTASMP LNLLPKHSNA STSLEQFCRD TVMTIWHYHG 480 GCQVGKVVDH DYKVLGVDAL RVVDGSTFYY SPGTNPQATV MMLGRYMGVR ILRERLASND 540 SK* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05199 | GMC_oxred_C | 3.0e-24 | 380 | 524 | 158 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR03970 | Rv0697 | 3.0e-31 | 49 | 524 | 527 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 1.0e-33 | 49 | 524 | 558 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 1.0e-41 | 48 | 539 | 562 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 3 | 536 | 572 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAL47442.1 | 0 | 14 | 536 | 12 | 569 | At1g12570/T12C24_9 [Arabidopsis thaliana] |
| EMBL | CBI34759.1 | 0 | 21 | 542 | 21 | 578 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002282510.1 | 0 | 36 | 542 | 1 | 544 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002298074.1 | 0 | 1 | 540 | 1 | 574 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509694.1 | 0 | 10 | 542 | 12 | 548 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 21 | 539 | 7 | 521 | A Chain A, Crystal Structure Of Soybean Beta-Amylase Mutant Substituted At Surface Region |
| PDB | 3gdp_A | 0 | 21 | 539 | 7 | 521 | A Chain A, Crystal Structure Of Soybean Beta-Amylase Mutant Substituted At Surface Region |
| PDB | 3gdn_B | 0 | 21 | 539 | 7 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 21 | 539 | 7 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 21 | 539 | 7 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
