| Basic Information | |
|---|---|
| Species | Citrus clementina |
| Cazyme ID | Ciclev10019803m |
| Family | GT47 |
| Protein Properties | Length: 506 Molecular Weight: 57985.7 Isoelectric Point: 9.6867 |
| Chromosome | Chromosome/Scaffold: 3 Start: 40056976 End: 40061574 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 117 | 426 | 0 |
| IRVYVYEMPRKFTYDLLWLFRNTYKDTSNLTSNGSPVHRLIEQHSIDYWLWADLIVPESERLLKNVVRVRRQEEADLFYIPFFTTISFFLLEKQECKALY RALKWVTDQPAWKRSEGRDHILPVHHPWSFKSVRRYVKNAIWLLPDMDSTGNWYKPGQVSLEKDLILPYVPNVDFCDVKCVSESESKRSTLLFFRGRLKR NAGGKIRAKLVAELSSAEGVVIEEGTAGEVGKAAAQNGMRRSIFCLNPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGILDYRKIALFVSSSDATQP GYLLKFLRGI | |||
| Full Sequence |
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| Protein Sequence Length: 506 Download |
| MALLKQTPLT IARSNAKSRI LLFTLFLFAF SLLFALFSLT RNPYSDPYPY PTPNAKPETS 60 FVASIERFLA QTSQRFRDDT VTSLTEDGVV RKFDDVASKI ERQRVYEDSY YPLSLPIRVY 120 VYEMPRKFTY DLLWLFRNTY KDTSNLTSNG SPVHRLIEQH SIDYWLWADL IVPESERLLK 180 NVVRVRRQEE ADLFYIPFFT TISFFLLEKQ ECKALYRALK WVTDQPAWKR SEGRDHILPV 240 HHPWSFKSVR RYVKNAIWLL PDMDSTGNWY KPGQVSLEKD LILPYVPNVD FCDVKCVSES 300 ESKRSTLLFF RGRLKRNAGG KIRAKLVAEL SSAEGVVIEE GTAGEVGKAA AQNGMRRSIF 360 CLNPAGDTPS SARLFDAIVS GCIPVIVSDE LELPFEGILD YRKIALFVSS SDATQPGYLL 420 KFLRGISPAQ IREMRRNLVQ YSRHFLYSSP AQPLGPEDLV WRMIAGKLVN IKLHTRRSQR 480 VVKESRSICT CDCRRANFTS TTSLS* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-66 | 116 | 426 | 320 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAY76230.1 | 0 | 49 | 490 | 53 | 488 | hypothetical protein OsI_04166 [Oryza sativa Indica Group] |
| RefSeq | NP_197191.1 | 0 | 14 | 495 | 13 | 497 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002285599.1 | 0 | 57 | 500 | 62 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325382.1 | 0 | 40 | 499 | 38 | 501 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002520033.1 | 0 | 46 | 502 | 45 | 505 | catalytic, putative [Ricinus communis] |
