Basic Information | |
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Species | Citrus clementina |
Cazyme ID | Ciclev10020045m |
Family | GT47 |
Protein Properties | Length: 466 Molecular Weight: 53881.9 Isoelectric Point: 10.0044 |
Chromosome | Chromosome/Scaffold: 3 Start: 41485985 End: 41488852 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 132 | 408 | 0 |
RSFRVYVYPHRRNDPFANVLLPVDFEPRGNYASESYFKKVFMKSHFVTKDPSKADLFFLPFSIARMRHDRRIGTEGIPDFISHYIFNISQKYPYWNRTGG ADHFYVACHSIGRSAMEKAWEVKLNAIQVVCSSSYFISGHIAHKDVSLPQIWPRQEDPPKLGSSKRNKLAFFAGAVNSPVREKLLQVWRNDSEIYAHSGR LKTPYADGLLGSKFCLHVKGFEVNTARIADSLYYGCVPVIIANHYDLPFADILNWKSFSIVVATLDIPLLKKILKGI |
Full Sequence |
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Protein Sequence Length: 466 Download |
MANNSSLILY FSRNRGLVKT FFFIPTTLAL LSTLFILFYI STTSHLFFNH HQRHHQHQLT 60 PFILKNNPLP PPLKSSPVLV SLLNVSNNSH GDGRVRNQRS VNVPMEANGN SMNKEVFHDR 120 DIFLEDYKQM NRSFRVYVYP HRRNDPFANV LLPVDFEPRG NYASESYFKK VFMKSHFVTK 180 DPSKADLFFL PFSIARMRHD RRIGTEGIPD FISHYIFNIS QKYPYWNRTG GADHFYVACH 240 SIGRSAMEKA WEVKLNAIQV VCSSSYFISG HIAHKDVSLP QIWPRQEDPP KLGSSKRNKL 300 AFFAGAVNSP VREKLLQVWR NDSEIYAHSG RLKTPYADGL LGSKFCLHVK GFEVNTARIA 360 DSLYYGCVPV IIANHYDLPF ADILNWKSFS IVVATLDIPL LKKILKGISS EEYLLLQNNV 420 LKVRKHFQWH VFPSDYDAFY MVMYDLWLRR SSVRVQWSTS LDSNW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-67 | 130 | 408 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABD28410.1 | 0 | 24 | 455 | 26 | 481 | Exostosin-like [Medicago truncatula] |
EMBL | CBI39073.1 | 0 | 118 | 455 | 108 | 445 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 113 | 462 | 101 | 450 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325425.1 | 0 | 130 | 464 | 1 | 331 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002525728.1 | 0 | 130 | 460 | 1 | 331 | catalytic, putative [Ricinus communis] |