Basic Information | |
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Species | Citrus clementina |
Cazyme ID | Ciclev10020650m |
Family | GT47 |
Protein Properties | Length: 375 Molecular Weight: 43640.1 Isoelectric Point: 9.6819 |
Chromosome | Chromosome/Scaffold: 3 Start: 41486209 End: 41488852 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 41 | 317 | 0 |
RSFRVYVYPHRRNDPFANVLLPVDFEPRGNYASESYFKKVFMKSHFVTKDPSKADLFFLPFSIARMRHDRRIGTEGIPDFISHYIFNISQKYPYWNRTGG ADHFYVACHSIGRSAMEKAWEVKLNAIQVVCSSSYFISGHIAHKDVSLPQIWPRQEDPPKLGSSKRNKLAFFAGAVNSPVREKLLQVWRNDSEIYAHSGR LKTPYADGLLGSKFCLHVKGFEVNTARIADSLYYGCVPVIIANHYDLPFADILNWKSFSIVVATLDIPLLKKILKGI |
Full Sequence |
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Protein Sequence Length: 375 Download |
MFRWKLMNLE TSGFYASGNS MNKEVFHDRD IFLEDYKQMN RSFRVYVYPH RRNDPFANVL 60 LPVDFEPRGN YASESYFKKV FMKSHFVTKD PSKADLFFLP FSIARMRHDR RIGTEGIPDF 120 ISHYIFNISQ KYPYWNRTGG ADHFYVACHS IGRSAMEKAW EVKLNAIQVV CSSSYFISGH 180 IAHKDVSLPQ IWPRQEDPPK LGSSKRNKLA FFAGAVNSPV REKLLQVWRN DSEIYAHSGR 240 LKTPYADGLL GSKFCLHVKG FEVNTARIAD SLYYGCVPVI IANHYDLPFA DILNWKSFSI 300 VVATLDIPLL KKILKGISSE EYLLLQNNVL KVRKHFQWHV FPSDYDAFYM VMYDLWLRRS 360 SVRVQWSTSL DSNW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-69 | 39 | 317 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABD28410.1 | 0 | 22 | 364 | 138 | 481 | Exostosin-like [Medicago truncatula] |
EMBL | CBI39073.1 | 0 | 27 | 364 | 108 | 445 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 14 | 371 | 92 | 450 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325425.1 | 0 | 39 | 373 | 1 | 331 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002525728.1 | 0 | 39 | 369 | 1 | 331 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
ES827236 | 279 | 87 | 365 | 0 |
JK517670 | 291 | 18 | 308 | 0 |
DT765011 | 261 | 111 | 371 | 0 |
AM713821 | 248 | 115 | 362 | 0 |
DY943505 | 267 | 71 | 336 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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