Basic Information | |
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Species | Citrus clementina |
Cazyme ID | Ciclev10029912m |
Family | GT47 |
Protein Properties | Length: 292 Molecular Weight: 34141.5 Isoelectric Point: 9.9414 |
Chromosome | Chromosome/Scaffold: 8 Start: 10511928 End: 10515920 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 20 | 239 | 2.60642e-43 |
KWRGNSSYQTPWKLKRKFAIEGYFFKKIRESRFLTTDPAKAHLFFIPVSCHKMRGKYPYLNRTQGADHFFVTCYDIGVRATEGFHNLWKNSIRVLCSRHK GVSLPQIIPPFLLYAGGNDFEDRTSLALWTGYSNYSKLKDLLAQFWQNDERQILSKFCICPGGSLGNFAQIVDSIHCGCVPVIISDFHDLPFNDILDWNK LSMIIREDDVHRLNLILKGI |
Full Sequence |
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Protein Sequence Length: 292 Download |
SEIYSDIFHS PETLKANMRK WRGNSSYQTP WKLKRKFAIE GYFFKKIRES RFLTTDPAKA 60 HLFFIPVSCH KMRGKYPYLN RTQGADHFFV TCYDIGVRAT EGFHNLWKNS IRVLCSRHKG 120 VSLPQIIPPF LLYAGGNDFE DRTSLALWTG YSNYSKLKDL LAQFWQNDER QILSKFCICP 180 GGSLGNFAQI VDSIHCGCVP VIISDFHDLP FNDILDWNKL SMIIREDDVH RLNLILKGII 240 SKGKFINSHK NTFKAQKQFE WNTPPIKYGT TFHMVVYELW LRRYFLKYRL S* 300 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-35 | 29 | 239 | 267 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195517.1 | 0 | 2 | 288 | 81 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 4 | 288 | 74 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303415.1 | 0 | 24 | 288 | 16 | 326 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002307304.1 | 0 | 5 | 288 | 65 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 1 | 288 | 61 | 406 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EH770778 | 281 | 21 | 251 | 0 |
EX317869 | 278 | 36 | 264 | 0 |
GT006581 | 243 | 74 | 288 | 0 |
GO268625 | 252 | 27 | 229 | 0 |
CX077756 | 243 | 74 | 288 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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