| Basic Information | |
|---|---|
| Species | Citrus clementina |
| Cazyme ID | Ciclev10031199m |
| Family | AA3 |
| Protein Properties | Length: 535 Molecular Weight: 58585.9 Isoelectric Point: 6.9471 |
| Chromosome | Chromosome/Scaffold: 4 Start: 23940023 End: 23941837 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 51 | 525 | 0 |
| GKSFDYIVVGGGTTGCPLAATLSDNFSVLLVERGGSPFGNPLVTDKRFFGFSLLQTDEYTSVAQSFISTDGIQNHRGRVLGGSSAINGGFYSRAREDFVK KAGWDEELIKKAYEWVESKVVFPPELTPWQSVVEFGLLEAGILPYNGYSLEHIEGTKIGGTAFDQCGKRHTSADLLEAGNPKNLVVLLNATVNNIIFSNN GKANESRAHGIRFIKSDGSSNHMHEAYLNKPGNSSTWGDVILSAGALGSPQLLLLSGIGPHDHLKDLNIPTIVDLQEVGEGMQDNPCIAKLVDTMPQKRL PEPPEVVGIADNFKFIIQAGVLPISFNASRMPIAAKLAFPISRGKLELDSTDPRQNPSIKFNYLAKEKDLDECVKMVQLLNKVTKSQSVSSFLGIKPQEK LMSNSDELRKLCKNNVRTFYHYHGGCIVGSVVDKDYRVYGVKGLRVIDGSTFQESPGTNPMATVMMLGRYQGVKL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 535 Download |
| MKFPDTFHSH ELLIAFSFFL LTLPLFSSSL PEGKGKEVPY YMTSDVKEVA GKSFDYIVVG 60 GGTTGCPLAA TLSDNFSVLL VERGGSPFGN PLVTDKRFFG FSLLQTDEYT SVAQSFISTD 120 GIQNHRGRVL GGSSAINGGF YSRAREDFVK KAGWDEELIK KAYEWVESKV VFPPELTPWQ 180 SVVEFGLLEA GILPYNGYSL EHIEGTKIGG TAFDQCGKRH TSADLLEAGN PKNLVVLLNA 240 TVNNIIFSNN GKANESRAHG IRFIKSDGSS NHMHEAYLNK PGNSSTWGDV ILSAGALGSP 300 QLLLLSGIGP HDHLKDLNIP TIVDLQEVGE GMQDNPCIAK LVDTMPQKRL PEPPEVVGIA 360 DNFKFIIQAG VLPISFNASR MPIAAKLAFP ISRGKLELDS TDPRQNPSIK FNYLAKEKDL 420 DECVKMVQLL NKVTKSQSVS SFLGIKPQEK LMSNSDELRK LCKNNVRTFY HYHGGCIVGS 480 VVDKDYRVYG VKGLRVIDGS TFQESPGTNP MATVMMLGRY QGVKLVEERR EICS* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05199 | GMC_oxred_C | 5.0e-33 | 390 | 518 | 136 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR03970 | Rv0697 | 1.0e-37 | 55 | 518 | 519 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 8.0e-44 | 55 | 518 | 546 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 2.0e-49 | 47 | 519 | 565 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 3.0e-165 | 53 | 529 | 541 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_172871.1 | 0 | 41 | 531 | 3 | 485 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
| RefSeq | XP_002312249.1 | 0 | 42 | 531 | 1 | 489 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002315047.1 | 0 | 35 | 528 | 1 | 489 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002315048.1 | 0 | 1 | 531 | 1 | 528 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002522448.1 | 0 | 1 | 529 | 1 | 525 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3gdp_B | 0 | 53 | 529 | 26 | 517 | A Chain A, Mannosyl-3-Phosphoglycerate Synthase From Rubrobacter Xylanophilus |
| PDB | 3gdp_A | 0 | 53 | 529 | 26 | 517 | A Chain A, Mannosyl-3-Phosphoglycerate Synthase From Rubrobacter Xylanophilus |
| PDB | 3gdn_B | 0 | 53 | 529 | 26 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 3gdn_A | 0 | 53 | 529 | 26 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| PDB | 1ju2_B | 0 | 53 | 529 | 26 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
