| Basic Information | |
|---|---|
| Species | Citrus clementina |
| Cazyme ID | Ciclev10033889m |
| Family | GT47 |
| Protein Properties | Length: 353 Molecular Weight: 40274.4 Isoelectric Point: 8.1991 |
| Chromosome | Chromosome/Scaffold: 4 Start: 484229 End: 485287 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 58 | 277 | 3e-34 |
| DSEPLFVSSLLNSSFLTLDPEQADLFFIPFSSINVSARSLSRLVNALRYDFPFWNRTLGADHFYVSCEGLSFGSDRNVLELKKNSVQISCFPTAPDKFVP HKDITLPPSLAGPYSPMEKAKNHLHLGYVRYGAIKEHSLIKELRADSEFLVDSEPLDQLGFQERIRISKFCLFEYGKGDVSGINDALRHGCVPVVITDRP IQDLPLMDVLRWQEMAVFVG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 353 Download |
| MFLTNIPLFI SLFLSFSLPL YSTPYLSPTT LFPNYQKMLQ SFKVFPYTSP LVFSTPSDSE 60 PLFVSSLLNS SFLTLDPEQA DLFFIPFSSI NVSARSLSRL VNALRYDFPF WNRTLGADHF 120 YVSCEGLSFG SDRNVLELKK NSVQISCFPT APDKFVPHKD ITLPPSLAGP YSPMEKAKNH 180 LHLGYVRYGA IKEHSLIKEL RADSEFLVDS EPLDQLGFQE RIRISKFCLF EYGKGDVSGI 240 NDALRHGCVP VVITDRPIQD LPLMDVLRWQ EMAVFVGWNK GRAGVKVEEL KRVLYRTCGG 300 DDRYGEVRGL GVTAGKHFVW NEQPQPYDAF HMVMYQLWLR RHTIRYARRE VA* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-22 | 76 | 276 | 230 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_001046127.1 | 0 | 15 | 346 | 57 | 402 | Os02g0187200 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002282317.1 | 0 | 10 | 350 | 17 | 358 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311191.1 | 0 | 8 | 350 | 8 | 343 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002316258.1 | 0 | 8 | 350 | 8 | 337 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524235.1 | 0 | 28 | 350 | 32 | 335 | conserved hypothetical protein [Ricinus communis] |
