| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre02.g099400.t1.3 |
| Family | GT47 |
| Protein Properties | Length: 967 Molecular Weight: 102238 Isoelectric Point: 8.3657 |
| Chromosome | Chromosome/Scaffold: 2 Start: 4351798 End: 4360116 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 491 | 906 | 5.6e-36 |
| AAEAVLTQNPWEANLFVVPTWSIWYSGNVASPAAVLRHVIAHLKAAYPFWDAMGGGRNHVFWASNDRGVCDWQELEPDLRTPIMVTHFGQAPRVPPFHIL SVLGDSSWRNVLRGHLQSALQREKVPVAKGFQPNTHADVQAEYAPCYRPEKDVLAPAVVPEWVMPYSDAVYGPRHDAFNHPAPHTAAGDGTEAGVSPGGA AGGGTAAGRGARNGGSSSSSSSSSSGSGSSSGGGGIKGGRLLAGSRSTTPPPGELPERNITLFFSGGIRPEQLYYSQGVRQAVMRMAAGGGGGGGGGGGG GGGGGGGKDGAAGGSVGDAGAAEASDDFRAWNRPDFVLSIAGRHSQTLMASSRFCLAPSGWGWGVRLLEAVACGCVPVVVQDQVYQPLWDVVPYDEFAVV LPRSQLHRLPQLLDAV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 967 Download |
| MKLLWHRAAM VVLVALACGN GSDAQLHASP FNKQLLNNDC HSDCTARGNC NGATGRCECP 60 FGLTGQACER RLLPACHTTA AAVTGSRPLY GTWSLKNCNC FRQLARIGCP PELRGECLYP 120 ALQGGPAVAC FEIEGAAEEE QTSDVPPEGF AHPSLAWYWG QPLLGRAAMN RTAPPRSHLL 180 PNGLYQLPLS ACPQRCHERG ICAAEQPLKA AAGREAGDRA TLGAELGADG VATGGRCICA 240 ASYTGTACDL AVQEDCYGSC NGGTCIQGFC HCPPGRWGLA CTNTERWNSS EGWLPSVAGP 300 RIYVYSLPQE VVHRVTNDGD TTRDGMYRGE ELFLQELFAA AATAAVKPRD LSSAAKALLS 360 SSTSQAAASP AHTEVQTRAA DQRKEKGKGA EAVTAHPRWP GDEGKEKVEG QSRPPKRKPR 420 QQQEFSGTSP PRTHGRHAHG HHHRRAAGHQ DGHSHHRARR MADTNEHRPA GSSSDSSSSS 480 SSSSSSGGLL AAEAVLTQNP WEANLFVVPT WSIWYSGNVA SPAAVLRHVI AHLKAAYPFW 540 DAMGGGRNHV FWASNDRGVC DWQELEPDLR TPIMVTHFGQ APRVPPFHIL SVLGDSSWRN 600 VLRGHLQSAL QREKVPVAKG FQPNTHADVQ AEYAPCYRPE KDVLAPAVVP EWVMPYSDAV 660 YGPRHDAFNH PAPHTAAGDG TEAGVSPGGA AGGGTAAGRG ARNGGSSSSS SSSSSGSGSS 720 SGGGGIKGGR LLAGSRSTTP PPGELPERNI TLFFSGGIRP EQLYYSQGVR QAVMRMAAGG 780 GGGGGGGGGG GGGGGGGKDG AAGGSVGDAG AAEASDDFRA WNRPDFVLSI AGRHSQTLMA 840 SSRFCLAPSG WGWGVRLLEA VACGCVPVVV QDQVYQPLWD VVPYDEFAVV LPRSQLHRLP 900 QLLDAVGPGQ LAALQAGLAR WHRAFLYRHH SPSGLAFNYT LAALRRRLVN LNSAHYRRSH 960 RRHRNL* 1020 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00180 | EGF_Lam | 0.006 | 39 | 70 | 32 | + Laminin-type epidermal growth factor-like domai. | ||
| pfam03016 | Exostosin | 9.0e-6 | 495 | 591 | 97 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 5.0e-8 | 838 | 906 | 70 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001694987.1 | 0 | 8 | 441 | 17 | 442 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694987.1 | 0 | 480 | 951 | 330 | 699 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699824.1 | 0 | 1 | 407 | 1 | 407 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699824.1 | 0 | 534 | 637 | 407 | 510 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699824.1 | 0 | 737 | 966 | 511 | 740 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
