| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre02.g105900.t1.2 |
| Family | CE10 |
| Protein Properties | Length: 613 Molecular Weight: 64202.4 Isoelectric Point: 5.2515 |
| Chromosome | Chromosome/Scaffold: 2 Start: 5214330 End: 5219131 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 94 | 265 | 6.00036e-42 |
| YESEDCLSLNVWAPANATATSKLPVRFYIHGGGFQQGSGSDDSYDGCRGASDGNVVMVTINYRLGILGFMALPELKDSAANGTVGNWGLLDQQLALKWVK DNIAAFGGDPNKMAVYGESAGAYSLLLHMVATGSKGLFSSAVSFSGSADAMAVDLLPDAYKKGQVVAAALNC | |||
| Full Sequence |
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| Protein Sequence Length: 613 Download |
| MGRFSLAAAA AGLLLGLASA LDTSVTVSLG KITGAHCASG ESVLSFKGIP FAEAPTGTRR 60 WAAPVAYGKI SKFPTAGLDA TNYGYMCPQG AGEYESEDCL SLNVWAPANA TATSKLPVRF 120 YIHGGGFQQG SGSDDSYDGC RGASDGNVVM VTINYRLGIL GFMALPELKD SAANGTVGNW 180 GLLDQQLALK WVKDNIAAFG GDPNKMAVYG ESAGAYSLLL HMVATGSKGL FSSAVSFSGS 240 ADAMAVDLLP DAYKKGQVVA AALNCSTASI ATARGYQDVA DCLRNSATPA SIGAIMATYL 300 TTTIQYLVPV VDGVVFTKHP VLLMREGKSA TVPITLVTNA REGILEISGE VQKNVSLDTS 360 ADFISIMRRF VSVPKSFAAK VATQYDKAKY GDSLYFSAIF ALTDVGYHCP ALRTASAMAA 420 QGLTVRLMQL QMARPTNGCP LQLGAGYPAY LYELWDAFHS YDIPFTFMIP YTAADVCNFT 480 SAERDLSSFM SGMVSAVAAT GAPVPARSAS LTAPQLLNLT WPAWTPLQSQ LILDMDVNAP 540 KLIDTADWKS TCQIWDDILS SNIALGTQDP DALPPPAARS PPPPPGSSAA VVVASAWALW 600 LPAALTALAL LF* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07859 | Abhydrolase_3 | 0.0001 | 140 | 215 | 83 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| COG0657 | Aes | 6.0e-5 | 104 | 284 | 184 | + Esterase/lipase [Lipid metabolism] | ||
| COG2272 | PnbA | 3.0e-68 | 41 | 503 | 473 | + Carboxylesterase type B [Lipid metabolism] | ||
| cd00312 | Esterase_lipase | 1.0e-84 | 42 | 503 | 487 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| pfam00135 | COesterase | 4.0e-101 | 25 | 555 | 551 | + Carboxylesterase family. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EER07696.1 | 0 | 24 | 556 | 56 | 632 | Acetylcholinesterase 1 precursor, putative [Perkinsus marinus ATCC 50983] |
| RefSeq | XP_001371375.1 | 0 | 22 | 559 | 111 | 637 | PREDICTED: similar to acetylcholinesterase collagen-tailed or globular form [Monodelphis domestica] |
| RefSeq | XP_001699975.1 | 0 | 428 | 585 | 1 | 158 | hypothetical protein CHLREDRAFT_166780 [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699976.1 | 0 | 25 | 250 | 1 | 244 | predicted protein [Chlamydomonas reinhardtii] |
| RefSeq | XP_002481288.1 | 0 | 23 | 558 | 17 | 550 | carboxylesterase, putative [Talaromyces stipitatus ATCC 10500] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2xuq_B | 0 | 25 | 559 | 10 | 536 | A Chain A, Crystal Structure Of Serine Hydroxymethyltransferase From Burkholderia Pseudomallei |
| PDB | 2xuq_A | 0 | 25 | 559 | 10 | 536 | A Chain A, Crystal Structure Of Serine Hydroxymethyltransferase From Burkholderia Pseudomallei |
| PDB | 2xup_B | 0 | 25 | 559 | 10 | 536 | A Chain A, Crystal Structure Of Serine Hydroxymethyltransferase From Burkholderia Pseudomallei |
| PDB | 2xup_A | 0 | 25 | 559 | 10 | 536 | A Chain A, Crystal Structure Of Serine Hydroxymethyltransferase From Burkholderia Pseudomallei |
| PDB | 2xuo_B | 0 | 25 | 559 | 10 | 536 | A Chain A, Crystal Structure Of Serine Hydroxymethyltransferase From Burkholderia Pseudomallei |
| Transmembrane Domains | |||||
|---|---|---|---|---|---|
| Start | End | ||||
| 589 | 611 | ||||
| Signal Peptide | |||||
|---|---|---|---|---|---|
| Cleavage Site | |||||
| 20 | |||||
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FC109875 | 142 | 430 | 571 | 0 |
| GW598220 | 273 | 25 | 284 | 8.40779e-45 |
| FD837888 | 202 | 373 | 567 | 2e-40 |
| GW598300 | 254 | 97 | 343 | 7e-36 |
| FC109875 | 57 | 388 | 441 | 0.00000000000001 |
| Orthologous Group | |||||
|---|---|---|---|---|---|
| Species | ID | ||||
| Ricinus communis | 30561.m000040 | ||||
| Volvox carteri | Vocar20013658m | ||||
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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