| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre02.g111150.t1.3 |
| Family | GT47 |
| Protein Properties | Length: 688 Molecular Weight: 78219.8 Isoelectric Point: 7.6378 |
| Chromosome | Chromosome/Scaffold: 2 Start: 5838878 End: 5845319 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 275 | 635 | 3.80032e-42 |
| ELKIYVYDLPQHVAYMRPLGDHWPLHHSIYLAEIELYHRLLGDTTVVTENPWEANLFYVPTHTYYYIGNIGFPGKLYTAVFHHVRQQYPWWNLTAGRNHV VSNSNDRGCCDLYRMGPDVQHPIKVVHFAQAPRHGVPLSRNRDKGREAEGEKPEHLAARLNSHVEDPAMQGAIAEMQHLDGRPRFRGFPLYELPALQQER EQCYRPEHDVAFPPYLSDREGNWFSVMKEAYDYTPDGKATFKRGVARDTLFYFNGFTKPDLAYSAGVRQGLLALFGNSTRADLSINKGGGSQRMLRSRFC FTPMGFGWGIRLSQAMLTGCVPIMVHDHVWPTLWDVLPYEQFSIRVSRHNMYRLLDYLESI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 688 Download |
| MRALLLCFLS LAFLSLITGQ QGEPLLRFFK EAKKSCAAGC EENGNCNAET GECQCRFGYG 60 GADCSQPILS GCLSARKKGA VPQYGLQFPK NCECYRQLLN ISCYGSDFAK DPFWCNQPAI 120 WEWHTIKCYE YMDVPPEQQL SDPPEAGSTK VVWRQGVRND SAHRDGGFLF QPYTKTDGLR 180 TQNLETLLPM DKCKDRCNER GRCVDAGGGL PQCVCAPFFT GPSCQLDDPS HCPLNCSGRG 240 RCDGGFCHCQ AGWWGAACTR SKAYTAEEWT PHPSELKIYV YDLPQHVAYM RPLGDHWPLH 300 HSIYLAEIEL YHRLLGDTTV VTENPWEANL FYVPTHTYYY IGNIGFPGKL YTAVFHHVRQ 360 QYPWWNLTAG RNHVVSNSND RGCCDLYRMG PDVQHPIKVV HFAQAPRHGV PLSRNRDKGR 420 EAEGEKPEHL AARLNSHVED PAMQGAIAEM QHLDGRPRFR GFPLYELPAL QQEREQCYRP 480 EHDVAFPPYL SDREGNWFSV MKEAYDYTPD GKATFKRGVA RDTLFYFNGF TKPDLAYSAG 540 VRQGLLALFG NSTRADLSIN KGGGSQRMLR SRFCFTPMGF GWGIRLSQAM LTGCVPIMVH 600 DHVWPTLWDV LPYEQFSIRV SRHNMYRLLD YLESITPQQL ARLQDGVAQW HKAFVWQPEV 660 GGLAYNYTLT SLHHRLLNMW TAFFRRF* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-14 | 276 | 405 | 133 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 3.0e-15 | 475 | 635 | 169 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693329.1 | 0 | 55 | 684 | 2 | 599 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694919.1 | 0 | 34 | 684 | 11 | 674 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694986.1 | 0 | 9 | 684 | 3 | 680 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694987.1 | 0 | 1 | 680 | 13 | 700 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699926.1 | 0 | 1 | 687 | 139 | 785 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
