| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre02.g116600.t2.1 |
| Family | GT47 |
| Protein Properties | Length: 575 Molecular Weight: 64677.1 Isoelectric Point: 8.1795 |
| Chromosome | Chromosome/Scaffold: 2 Start: 6511045 End: 6516819 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 138 | 438 | 4.4e-39 |
| KRGPNIYIYEVPPEYHVKRDIHKVDRPPLQLAFMERILSGGHRTHNPEEADFFYIPGSSRDLKKAFLLQPLLAYISTTWPFWNATGGARHIMPAEGDVGT CELPLKVRLFTANVTWLQFWGMYDFHPHWTQIFHNRIPCMVPGRDIVVPFMAMSSHDRFVIETPLHPRNQKRNRTNTFFFAGGVCGSGNKRALPPHCTYY KQVRYSGGVRQAVYLHFHNRTGWRVVPGTDDYARDYASSRFCLAAAGGGWGKRGIVAAMYGCIPVAATDMLYEAFEPEMDWGRFGVRITQAEIPQLADKL E | |||
| Full Sequence |
|---|
| Protein Sequence Length: 575 Download |
| MREKRFCATA AALLLGLALL PLLQPAIGQK ACPEGCSKFG TCNLELGRCD CPWNYTGDAC 60 QTHNPAGFCV KRLGVDNPIN TCKDGDPTLC VNACNGRGDC KGGFCHCKEG YFGTDCALSY 120 NDQGKIEVLA GLNYRLNKRG PNIYIYEVPP EYHVKRDIHK VDRPPLQLAF MERILSGGHR 180 THNPEEADFF YIPGSSRDLK KAFLLQPLLA YISTTWPFWN ATGGARHIMP AEGDVGTCEL 240 PLKVRLFTAN VTWLQFWGMY DFHPHWTQIF HNRIPCMVPG RDIVVPFMAM SSHDRFVIET 300 PLHPRNQKRN RTNTFFFAGG VCGSGNKRAL PPHCTYYKQV RYSGGVRQAV YLHFHNRTGW 360 RVVPGTDDYA RDYASSRFCL AAAGGGWGKR GIVAAMYGCI PVAATDMLYE AFEPEMDWGR 420 FGVRITQAEI PQLADKLEAY SEAEVARMQE RTACAAQHLH WSTNLGGIMG ETGEFDAFNT 480 IMAILRMRRK RPDLKPEQYY DQDEDFKNFI DCKPYDPQAA APPLCTMFIS PLYTKFDDTC 540 PAKHFRYYMR RKMGPPGGAI CVDAKDLASC RRFD* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.001 | 33 | 60 | 28 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 6.0e-35 | 138 | 440 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693540.1 | 0 | 32 | 522 | 5 | 506 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699869.1 | 0 | 1 | 472 | 1 | 427 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702517.1 | 0 | 34 | 487 | 13 | 479 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 16 | 513 | 57 | 554 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 41 | 513 | 3 | 472 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
