| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre02.g144050.t1.2 |
| Family | GT47 |
| Protein Properties | Length: 714 Molecular Weight: 81034.6 Isoelectric Point: 8.0798 |
| Chromosome | Chromosome/Scaffold: 2 Start: 7485261 End: 7493527 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 280 | 640 | 4.06377e-44 |
| HAKIKVYVYDLPSNVVHRREFHDQWSLIDLMYNAELEFTELLLGDWGVRTENPWEAALFYVPTFTYWYTGNVGHPYFVIQHATKWLQENSPFFNLTGGRN HIFWATNDRGVCKLQMAPPEMQHSIKLVHFGQSPRRPYAARMKVGQTTDPTAHLALRGALPQPGTRFPEFPAEFTAMDILEESEICIRPEKDVVTPNYIM PTWVEPHNYNQVWNVTQLPDGTRQVTRKRGPDVPVRNLTLYFAGFTKPQMSYSQGVRQLIHKLFGPGGKYDPKGPNARPDYKVGGPGGGEAATYMQQSRF CLAPMGSGWGIRLVEAMISGCVPVIIQDHVYQAHWDVVPFPEFSIRVGRHDLHRLVELLDD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 714 Download |
| MFGVLLLCGV LCSSAISPFK EHLKACHPDC TKFGNCNGET GQCDCPFGLT GPSCQERLFP 60 ACHVSKDPGT LPHYGTWYPK NCECIKQLHA WPGSCPEHLH YEGTGVSGAS PCFYDLVLAH 120 RFLCYRYQGR APADQLSDSP ALNASGVDWF HATGHTARHS PPQEAQLPPE QVPQEYKTPD 180 GGQWRPLSEC PDRCNNRGWC QIQGSNYQGR HYDAAERWCN CQGYFRGNSC EVADTQHCYR 240 GCSGVGECVG GWCHCKPGYW GHGCTRTKAY SSSVGWRPNH AKIKVYVYDL PSNVVHRREF 300 HDQWSLIDLM YNAELEFTEL LLGDWGVRTE NPWEAALFYV PTFTYWYTGN VGHPYFVIQH 360 ATKWLQENSP FFNLTGGRNH IFWATNDRGV CKLQMAPPEM QHSIKLVHFG QSPRRPYAAR 420 MKVGQTTDPT AHLALRGALP QPGTRFPEFP AEFTAMDILE ESEICIRPEK DVVTPNYIMP 480 TWVEPHNYNQ VWNVTQLPDG TRQVTRKRGP DVPVRNLTLY FAGFTKPQMS YSQGVRQLIH 540 KLFGPGGKYD PKGPNARPDY KVGGPGGGEA ATYMQQSRFC LAPMGSGWGI RLVEAMISGC 600 VPVIIQDHVY QAHWDVVPFP EFSIRVGRHD LHRLVELLDD VAPQELEELQ AGIERYHRAF 660 FWDAQWGGLA YNYTIQALKQ RAHSMWSANY RRRRRAQQRR RLFSVGRRSR HGW* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.009 | 29 | 54 | 26 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| COG0438 | RfaG | 0.004 | 569 | 664 | 100 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| cd03798 | GT1_wlbH_like | 0.002 | 569 | 670 | 112 | + This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS. | ||
| pfam03016 | Exostosin | 1.0e-25 | 280 | 638 | 366 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001694919.1 | 0 | 24 | 690 | 11 | 674 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694986.1 | 0 | 1 | 713 | 5 | 703 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694987.1 | 0 | 14 | 686 | 36 | 700 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699824.1 | 0 | 4 | 688 | 14 | 728 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699926.1 | 0 | 6 | 692 | 154 | 784 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
