| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre02.g144050.t2.1 |
| Family | GT47 |
| Protein Properties | Length: 718 Molecular Weight: 81362.9 Isoelectric Point: 8.0194 |
| Chromosome | Chromosome/Scaffold: 2 Start: 7485261 End: 7493527 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 284 | 644 | 4.06377e-44 |
| HAKIKVYVYDLPSNVVHRREFHDQWSLIDLMYNAELEFTELLLGDWGVRTENPWEAALFYVPTFTYWYTGNVGHPYFVIQHATKWLQENSPFFNLTGGRN HIFWATNDRGVCKLQMAPPEMQHSIKLVHFGQSPRRPYAARMKVGQTTDPTAHLALRGALPQPGTRFPEFPAEFTAMDILEESEICIRPEKDVVTPNYIM PTWVEPHNYNQVWNVTQLPDGTRQVTRKRGPDVPVRNLTLYFAGFTKPQMSYSQGVRQLIHKLFGPGGKYDPKGPNARPDYKVGGPGGGEAATYMQQSRF CLAPMGSGWGIRLVEAMISGCVPVIIQDHVYQAHWDVVPFPEFSIRVGRHDLHRLVELLDD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 718 Download |
| MFGVLLLCGV LCSSAISPFK EHLKACHPDC TKFGNCNGET GQCDCPFGLT GPSCQERLFP 60 ACHVSKDPGT LPHYGTWYPK NCECIKQLHA WPGSCPEHLH YEGTGVSGAS PCFYDLVLAH 120 RFLCYRYQGR APADQLSDSP ALNASGVDWF HATGHTARHS PPQEAQLPPE QVPQEYKTPD 180 GGQWRPLSEC PDRCNNRGWC QIQGSNYQGR HYDAAERWCN CQGYFRGNSC EVADTQHCYR 240 GCSGVGDGVG ECVGGWCHCK PGYWGHGCTR TKAYSSSVGW RPNHAKIKVY VYDLPSNVVH 300 RREFHDQWSL IDLMYNAELE FTELLLGDWG VRTENPWEAA LFYVPTFTYW YTGNVGHPYF 360 VIQHATKWLQ ENSPFFNLTG GRNHIFWATN DRGVCKLQMA PPEMQHSIKL VHFGQSPRRP 420 YAARMKVGQT TDPTAHLALR GALPQPGTRF PEFPAEFTAM DILEESEICI RPEKDVVTPN 480 YIMPTWVEPH NYNQVWNVTQ LPDGTRQVTR KRGPDVPVRN LTLYFAGFTK PQMSYSQGVR 540 QLIHKLFGPG GKYDPKGPNA RPDYKVGGPG GGEAATYMQQ SRFCLAPMGS GWGIRLVEAM 600 ISGCVPVIIQ DHVYQAHWDV VPFPEFSIRV GRHDLHRLVE LLDDVAPQEL EELQAGIERY 660 HRAFFWDAQW GGLAYNYTIQ ALKQRAHSMW SANYRRRRRA QQRRRLFSVG RRSRHGW* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0438 | RfaG | 0.006 | 573 | 668 | 100 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| pfam07974 | EGF_2 | 0.005 | 29 | 54 | 26 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| cd03798 | GT1_wlbH_like | 0.002 | 573 | 674 | 112 | + This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS. | ||
| pfam03016 | Exostosin | 1.0e-25 | 284 | 642 | 366 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001694919.1 | 0 | 24 | 694 | 11 | 674 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694986.1 | 0 | 1 | 717 | 5 | 703 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694987.1 | 0 | 14 | 690 | 36 | 700 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699824.1 | 0 | 4 | 692 | 14 | 728 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699926.1 | 0 | 6 | 696 | 154 | 784 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
