| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre02.g144100.t1.2 |
| Family | GT47 |
| Protein Properties | Length: 722 Molecular Weight: 81507.8 Isoelectric Point: 7.0905 |
| Chromosome | Chromosome/Scaffold: 2 Start: 7477421 End: 7484852 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 298 | 654 | 6.44597e-44 |
| HAEIKVYVYDLPNNVVHRREFNDQWALIDLMYNSELEFTDKLLGDWGVRTENPWEAALFYVPTFTYWFTGNVGHPYYVIQHATKWLQENSPFFNLTGGRN HIFWATNDRGVCKLQLAPPEMQHSIKLVHFGQSPRRPYAHRLKGQMDATAHLGGLLGALPQPGSRFPDFPEFNAGDILEESEICYRPEKDVVAPNYLHND WVKPDSYNKVWVTTTEADGTRVVKRKPDAPARTTTLYFGGYTKPIMAYSQGVRQTIHKMFGPGGKYDPEGPNARKDFVIGGPAGGAAVDSMKLAKFCLAP MGAGWGIRLAEAMVSGCVPVIIQDHIYQAHWDILPFEEFSIRIGRNELHQLVDILDD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 722 Download |
| MGTSRNARGS LGFRGGVACF LIVASCLASL SAVQGAAQSP FKEEIKTCHP DCTKFGNCNG 60 ETGQCDCPFG LTGPSCQERL FPACHSSKDE GTVPHYGTWY PKNCECIKQL RDWPGSCPDY 120 LHYEGNSAAF LSPCFYDSVT HHNLLCFSYK GRDPAEQLSD SPPLDDPNVE WFHITGYPRV 180 LMTPVPPAQW PKEYKTPDGG QWRPLSECPD RCNNRGWCQI QGSNYQGFHE DPKERWCNCH 240 GYYEGKSCEI ADPGHCYRNC SGVGECVGGW CHCKPGYWGH GCTRTKAYSS SVGWRPNHAE 300 IKVYVYDLPN NVVHRREFND QWALIDLMYN SELEFTDKLL GDWGVRTENP WEAALFYVPT 360 FTYWFTGNVG HPYYVIQHAT KWLQENSPFF NLTGGRNHIF WATNDRGVCK LQLAPPEMQH 420 SIKLVHFGQS PRRPYAHRLK GQMDATAHLG GLLGALPQPG SRFPDFPEFN AGDILEESEI 480 CYRPEKDVVA PNYLHNDWVK PDSYNKVWVT TTEADGTRVV KRKPDAPART TTLYFGGYTK 540 PIMAYSQGVR QTIHKMFGPG GKYDPEGPNA RKDFVIGGPA GGAAVDSMKL AKFCLAPMGA 600 GWGIRLAEAM VSGCVPVIIQ DHIYQAHWDI LPFEEFSIRI GRNELHQLVD ILDDVSPQQL 660 DSLQAGIERY HRAFFWDAHW GGLAYNYTVQ ALKRRAVSLW SANYRRHRRR LQHEREALEQ 720 D* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.009 | 51 | 76 | 26 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 3.0e-27 | 301 | 652 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001694919.1 | 0 | 46 | 704 | 11 | 674 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694986.1 | 0 | 16 | 704 | 4 | 680 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694987.1 | 0 | 1 | 700 | 1 | 700 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699824.1 | 0 | 17 | 702 | 8 | 728 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001699926.1 | 0 | 13 | 706 | 139 | 784 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
