| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre03.g158800.t3.1 |
| Family | CE1 |
| Protein Properties | Length: 295 Molecular Weight: 32148.2 Isoelectric Point: 6.4 |
| Chromosome | Chromosome/Scaffold: 3 Start: 2381131 End: 2384202 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 26 | 290 | 0 |
| SSSLGCEMTFTIYYPPAAAGGKVPVLYFLSGLTCNDENFITKIWHMCMTGAQRQAAARGVALIAPDTSPRGLGVEGESESWDFGVGAGFYVNATQPKWKN WRMYEYVTEELPALLRAAPLGSSLDLDRASVFGHSMGGHGALVVGLRNPTRFRTISAFSPISNPINAPWGVKAFTGYLGEDKAAWKEYDASELLRGFNGD VKPAILVDTGSADKFLTEQLKPDSLEAAAKESGYGNVTVRMQDGYDHSYFFISSFIDDHINFHAD | |||
| Full Sequence |
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| Protein Sequence Length: 295 Download |
| MATPEVSEVA VNKQFGGFNR RYKHKSSSLG CEMTFTIYYP PAAAGGKVPV LYFLSGLTCN 60 DENFITKIWH MCMTGAQRQA AARGVALIAP DTSPRGLGVE GESESWDFGV GAGFYVNATQ 120 PKWKNWRMYE YVTEELPALL RAAPLGSSLD LDRASVFGHS MGGHGALVVG LRNPTRFRTI 180 SAFSPISNPI NAPWGVKAFT GYLGEDKAAW KEYDASELLR GFNGDVKPAI LVDTGSADKF 240 LTEQLKPDSL EAAAKESGYG NVTVRMQDGY DHSYFFISSF IDDHINFHAD ALTK* 300 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12697 | Abhydrolase_6 | 5.0e-5 | 150 | 276 | 131 | + Alpha/beta hydrolase family. This family contains alpha/beta hydrolase enzymes of diverse specificity. | ||
| pfam00756 | Esterase | 3.0e-40 | 26 | 287 | 273 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 3.0e-64 | 15 | 292 | 306 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 5.0e-118 | 15 | 292 | 279 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 3.0e-169 | 2 | 294 | 293 | + S-formylglutathione hydrolase | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABK22177.1 | 0 | 7 | 292 | 5 | 280 | unknown [Picea sitchensis] |
| GenBank | ACJ11734.1 | 0 | 7 | 292 | 6 | 282 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| RefSeq | NP_181684.1 | 0 | 6 | 292 | 5 | 282 | SFGH (S-FORMYLGLUTATHIONE HYDROLASE); S-formylglutathione hydrolase/ hydrolase, acting on ester bonds [Arabidopsis thaliana] |
| RefSeq | XP_001697508.1 | 0 | 1 | 294 | 1 | 288 | esterase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001763419.1 | 0 | 9 | 293 | 1 | 276 | predicted protein [Physcomitrella patens subsp. patens] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3s8y_A | 0 | 6 | 293 | 4 | 279 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 6 | 293 | 4 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 6 | 293 | 4 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3fcx_B | 0 | 6 | 293 | 3 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 6 | 293 | 3 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| FC102541 | 213 | 1 | 213 | 0 |
| DV157903 | 287 | 7 | 292 | 0 |
| EX311356 | 286 | 7 | 292 | 0 |
| EX395493 | 286 | 7 | 292 | 0 |
| EX359119 | 286 | 7 | 292 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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