y
Basic Information | |
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Species | Chlamydomonas reinhardtii |
Cazyme ID | Cre03.g204050.t1.3 |
Family | GT47 |
Protein Properties | Length: 768 Molecular Weight: 86217.3 Isoelectric Point: 7.4036 |
Chromosome | Chromosome/Scaffold: 3 Start: 7657450 End: 7665300 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 329 | 679 | 0 |
RRPLIYVYDMEPLYNAKMLQYRLASAWCTHRFYTSGNGTAYSPWCYGVESGLHEYLLLSEHRTFDPEEADFFYVPVYISCLIWPVLNYADFPVFYSNGGT RVMHAVNMLSEARDWIDANYPFWKRRGGRDHIWTFPHDEGACWAPNSIVSSIWLTHWGRMDPDHTSKSSFDADNYTRDFVSPRQPKGYTHLIQGHGCYDP KKDLVIPIWRPPLHYARSPLQGAPAKPRDIFLFFRGDVGKKRSMLYSRGVRQKIYNMSIANNWRQKYNVLVGDGQDVQGDYSDLLSRSLFCLVATGDGWS ARTEDAVLHGCIPVVVIDGVHMKFETLFDVDSFSIRIPEADVANILTILKA |
Full Sequence |
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Protein Sequence Length: 768 Download |
MAKLSPFARA RWRLRQWCLL LQVTQLVIAV QPGGVGQLGG QQQERPWQLG EDTPVQTRCA 60 KTKGTWCTDF FGQAPVTWKT APRGSTECEG GCNNVGRCNY DTGYCDCAAG WTGPGCKTRQ 120 KRPCTNHFRT PEDPSTEPRS HIGPDKRDLN WTEPGVTPSR CYGVCDDDLG LCYCDGPLGR 180 IPAPDDAPPG TPPRRRGRPL MNQFEQPTTT YDGKPTWGGG TPYEKVYGPE GYCNVTHSPW 240 KPNCGGPEDL GGDYCDQPNE AFCPGGCSGH GACNLGFCIC DEGYYGHDCA RRKAGMPLLP 300 SRIPTTPWLS REVHEPRAAL EPPPSATRRR PLIYVYDMEP LYNAKMLQYR LASAWCTHRF 360 YTSGNGTAYS PWCYGVESGL HEYLLLSEHR TFDPEEADFF YVPVYISCLI WPVLNYADFP 420 VFYSNGGTRV MHAVNMLSEA RDWIDANYPF WKRRGGRDHI WTFPHDEGAC WAPNSIVSSI 480 WLTHWGRMDP DHTSKSSFDA DNYTRDFVSP RQPKGYTHLI QGHGCYDPKK DLVIPIWRPP 540 LHYARSPLQG APAKPRDIFL FFRGDVGKKR SMLYSRGVRQ KIYNMSIANN WRQKYNVLVG 600 DGQDVQGDYS DLLSRSLFCL VATGDGWSAR TEDAVLHGCI PVVVIDGVHM KFETLFDVDS 660 FSIRIPEADV ANILTILKAL PEERVRAMQA NLGQVWHRYR YADLPGIADT TRATQASNAA 720 DPLVREAAEL SKSAEPRFPR PFRGDPAVDD AFATIIQWLH SRIPDTR* 780 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-48 | 328 | 679 | 356 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001691329.1 | 0 | 55 | 767 | 80 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001693194.1 | 0 | 75 | 767 | 6 | 661 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001693195.1 | 0 | 1 | 767 | 1 | 659 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001697525.1 | 0 | 135 | 698 | 11 | 593 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001700890.1 | 0 | 73 | 767 | 10 | 703 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |