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Basic Information | |
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Species | Chlamydomonas reinhardtii |
Cazyme ID | Cre03.g205250.t1.3 |
Family | GT47 |
Protein Properties | Length: 627 Molecular Weight: 71272.6 Isoelectric Point: 8.0607 |
Chromosome | Chromosome/Scaffold: 3 Start: 7532484 End: 7541239 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 242 | 549 | 0 |
KLKIYMYDLPWDVAFPGAYNDGFFGRDPMYSAYELFMRYFLQDNVTRTENPWEANLFYVPMLLYFYIGNVRDAVPQTAWAINHVRSRWPFWDRSGGRDHF YFMTGDRGTCHLPRELQDQAIKVVHWGMQVAGTDWIGLDNKDYACIQLKRDLVVPPINMFAEILPTDTVKHYQTVVANGGQDFGRTLLFFFAGGIAQSME YSGGTRQAIKELLTSVHIANGNSTPADVVFVEGRTQEYKKLLLTSKFCIAPYGFGWGLRLVQAIEFGCIPVIIQDHVYQAFEDFLPYEEFSVRLPLRDVP RLLDILRS |
Full Sequence |
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Protein Sequence Length: 627 Download |
MCPWGYEGPA CEVDRMAACR VSTEDPGSCS NLYTRNCECY RACARLYCHD PNKADRCTHE 60 LGADMTRNRC WLRSDWQGGS TGPAGSELPE DWSRGGTTWY KHFAPQETRA SYDSDPGLLE 120 DKALWGSSNW RGNHSVLPPA ACPGRCSGRG VCFRWEHEQY PRCICAKGYN GTECAGVDSS 180 EACWFSPDCG GRGACKGGFC HCRPGFWGAG CHRGQGYLVQ RSAPPASATQ PPVWPDLRSP 240 TKLKIYMYDL PWDVAFPGAY NDGFFGRDPM YSAYELFMRY FLQDNVTRTE NPWEANLFYV 300 PMLLYFYIGN VRDAVPQTAW AINHVRSRWP FWDRSGGRDH FYFMTGDRGT CHLPRELQDQ 360 AIKVVHWGMQ VAGTDWIGLD NKDYACIQLK RDLVVPPINM FAEILPTDTV KHYQTVVANG 420 GQDFGRTLLF FFAGGIAQSM EYSGGTRQAI KELLTSVHIA NGNSTPADVV FVEGRTQEYK 480 KLLLTSKFCI APYGFGWGLR LVQAIEFGCI PVIIQDHVYQ AFEDFLPYEE FSVRLPLRDV 540 PRLLDILRSY SPEQQAALRL GMAKYYRAFV WHREFGGEAY EWTLAGLQRR LDTLQAQLFR 600 RRRHSSSRRS RRSLMTWHRP GRQRAG* 660 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-31 | 239 | 532 | 310 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001693329.1 | 0 | 1 | 626 | 1 | 626 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001693348.1 | 0 | 247 | 599 | 1 | 347 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001694986.1 | 0 | 2 | 594 | 49 | 675 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001694987.1 | 0 | 2 | 594 | 67 | 699 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001699926.1 | 0 | 211 | 601 | 341 | 784 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
AV636880 | 155 | 365 | 519 | 0 |
FD886287 | 266 | 293 | 558 | 0 |
FC093053 | 285 | 231 | 513 | 0 |
FD897421 | 150 | 450 | 599 | 0 |
FD881422 | 134 | 466 | 599 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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