| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre05.g233450.t1.2 |
| Family | GT47 |
| Protein Properties | Length: 486 Molecular Weight: 54364.2 Isoelectric Point: 8.4222 |
| Chromosome | Chromosome/Scaffold: 5 Start: 305123 End: 313268 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 58 | 353 | 8.39938e-42 |
| GPRIYIYELPPRFTTHKNLDKFDRPLYAHLWKRIISSGHRTLDGGAADYYYIPVDFRYLFGEAAQVLSYVADTWPWWNATGGARHLLLSTSDLGGCEGKQ LMRIRNATSQSVWVTPWGLTRKHPRVWWPGCHRPGLDVVIPIPAQTPNMLMTPLNPKVKPMERNITFYFAGKICGDNKDPKSDTSAWPICQTPTNPLYSA GMRQAVYFHHSKRPGYVIVPRSRTYVADMSSARFCLAPTGGGHGKRQVLVARFGCVPVPVTDWVLQPYEPELDWAAFSVPVAEADVPRMHEILAAI | |||
| Full Sequence |
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| Protein Sequence Length: 486 Download |
| MAETPLRCLN ACNGRGKCYA GWCHCQEGYY GADCSLSLDG QGRPQQLAGM GYAPAPGGPR 60 IYIYELPPRF TTHKNLDKFD RPLYAHLWKR IISSGHRTLD GGAADYYYIP VDFRYLFGEA 120 AQVLSYVADT WPWWNATGGA RHLLLSTSDL GGCEGKQLMR IRNATSQSVW VTPWGLTRKH 180 PRVWWPGCHR PGLDVVIPIP AQTPNMLMTP LNPKVKPMER NITFYFAGKI CGDNKDPKSD 240 TSAWPICQTP TNPLYSAGMR QAVYFHHSKR PGYVIVPRSR TYVADMSSAR FCLAPTGGGH 300 GKRQVLVARF GCVPVPVTDW VLQPYEPELD WAAFSVPVAE ADVPRMHEIL AAINDTALAR 360 MQRAVACASK HLWWSSMWGG LFGDDGRYDA FATLMEILRV RAAHPGTPPE RYRLVDERFR 420 RFADCELDDE PPAGVRLCTY GYDRDLVRLA PTPYCGWREY GKWGIPGGAI CEGADNIAQC 480 PRPWQ* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.003 | 10 | 34 | 27 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 2.0e-37 | 60 | 353 | 316 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693540.1 | 0 | 8 | 484 | 64 | 509 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702214.1 | 0 | 1 | 485 | 1 | 393 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702517.1 | 0 | 4 | 400 | 64 | 479 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 8 | 444 | 128 | 570 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 4 | 437 | 48 | 480 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FD821819 | 185 | 302 | 486 | 0 |
| FD838948 | 277 | 129 | 395 | 0 |
| AV627636 | 152 | 4 | 151 | 5e-35 |
| BI532593 | 142 | 286 | 426 | 8e-35 |
| BI532624 | 139 | 289 | 426 | 1e-33 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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