| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre06.g311950.t1.3 |
| Family | GT47 |
| Protein Properties | Length: 816 Molecular Weight: 90330.2 Isoelectric Point: 6.8429 |
| Chromosome | Chromosome/Scaffold: 6 Start: 9005696 End: 9011607 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 366 | 720 | 0 |
| RRPLIYVYDLPAAYNSRMLQYRNDRGMCTWRAFGSRNHTETFAWTYGLEVLMHEMLLQSEHRTFDPEAADFFYVPVYGSCFIFPLHCYADGPWWYAPSGP RVMHVTNMMLEVRDLIRKHFPYWDRRGGRDHIWLMTHDEGACYAPSDIYGSSIFLTHWGRRDSDHKSNTAFTPDNYTQEYVHPMQDKGWLHLIEGHPCYT PGKDLIVPALKLPHHFSGSPLLFHPPRPRDILLYLRGDVGKHRLPNYSRGIRQRLYKLWKDHDWQNKYNAMIGDGSDVPGGYSEHLASSKFCVVAPGDGW SARLEDAVLHGCVPVIVMDNVSAVFEEQLDFNSFSIRVGEAEAELAYLPERLKSV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 816 Download |
| MRPVTAAAAC LLLVLCRLSL GLESVPRDTP WSSGPDLPLE SALHWLGADA DAENVVSADT 60 GDHHGRQLLQ VGAGATGRDL ERRCRSTRGG WCGKLDALAP VPLKPALRGN KTCPRNCSGV 120 GNCNYDTGTC DCPAGSQGVD CGTVLLRPCT TAFRHTGDTP VGHIDDEGRD LNWRDEGYTE 180 SRCTGICDPV TARCFCDGKY RRVNPPKGSL PGTPAPVRGR PLGNHLCQVS DDGKGHKLEW 240 GQVPFEQIYG PDGWCNSDQP VIKCGCMFDG FAGELCEEVT ETMCVNQCSG HGDCDSGFCK 300 CHPGWYGTDC ARKASGLAME PGLHVSGTRP WLAETVVVSP EAAAASAAGA SMARGSGAMP 360 LHGAARRPLI YVYDLPAAYN SRMLQYRNDR GMCTWRAFGS RNHTETFAWT YGLEVLMHEM 420 LLQSEHRTFD PEAADFFYVP VYGSCFIFPL HCYADGPWWY APSGPRVMHV TNMMLEVRDL 480 IRKHFPYWDR RGGRDHIWLM THDEGACYAP SDIYGSSIFL THWGRRDSDH KSNTAFTPDN 540 YTQEYVHPMQ DKGWLHLIEG HPCYTPGKDL IVPALKLPHH FSGSPLLFHP PRPRDILLYL 600 RGDVGKHRLP NYSRGIRQRL YKLWKDHDWQ NKYNAMIGDG SDVPGGYSEH LASSKFCVVA 660 PGDGWSARLE DAVLHGCVPV IVMDNVSAVF EEQLDFNSFS IRVGEAEAEL AYLPERLKSV 720 PPRILEGMQK KLRTIWHRYA YVSHPLIASE AQRVIDNNVA MWRQKILADM AAGTAGPEAA 780 ERLTTRLGDR ATYPVQDDAF HTILQWLASR IADTR* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.003 | 286 | 310 | 27 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 6.0e-52 | 366 | 720 | 357 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001691329.1 | 0 | 1 | 815 | 1 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001697121.1 | 0 | 37 | 815 | 58 | 801 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698039.1 | 0 | 80 | 815 | 109 | 809 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698117.1 | 0 | 1 | 815 | 1 | 800 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001700890.1 | 0 | 99 | 815 | 11 | 703 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
