| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre07.g322884.t1.2 |
| Family | GT1 |
| Protein Properties | Length: 559 Molecular Weight: 60055.9 Isoelectric Point: 7.9094 |
| Chromosome | Chromosome/Scaffold: 7 Start: 1406680 End: 1410995 |
| Description | UDP-glucosyl transferase 71B5 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT1 | 204 | 502 | 2.7003e-42 |
| IAFESRMMAVPPALLMPVMPIMLPYKMDFAAAVQNTLMTLLFEAKPCRTFLDIMDECRALGGLVPGSFRQSLTRRPQPLLLIPAAPGFEPPVALPPHVRV VGGMLFESGPMSDKIREYLESDPGTPVIYVGFGSFVDFPDPTYALILRALGRVPARVLWSLKPKSAPSVMAAIANGTAPANVRVEPWVQQLAVLRHPAVK AVVTHGGFSSVSEIMYVGKPMVAIPGFGDNEHNAWKLQQLGAAVQLSKESPQLEQQLVEAVNKVLTDPSYTAAARRLGLVTRTAPGAPHAAALVEQVAA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 559 Download |
| MRTLRETCVC NAQRGIFLAL LVSVIANAKL LEEQVQAILE SEAPIGSQPL PAFRVLLLAL 60 PYAAHSLPLL RLGQELASRG NAVFFGSTDD YVELPYGKQV DFAALGVTWL PLGAPLHNAS 120 QRHEREQWAV EHWDSNNPDN AFRNSTGVLM REFHVVFLNG LAKTHKLGPG SFDVVITDFL 180 TSAGHDYAEY IGAPLVVFNS LSYIAFESRM MAVPPALLMP VMPIMLPYKM DFAAAVQNTL 240 MTLLFEAKPC RTFLDIMDEC RALGGLVPGS FRQSLTRRPQ PLLLIPAAPG FEPPVALPPH 300 VRVVGGMLFE SGPMSDKIRE YLESDPGTPV IYVGFGSFVD FPDPTYALIL RALGRVPARV 360 LWSLKPKSAP SVMAAIANGT APANVRVEPW VQQLAVLRHP AVKAVVTHGG FSSVSEIMYV 420 GKPMVAIPGF GDNEHNAWKL QQLGAAVQLS KESPQLEQQL VEAVNKVLTD PSYTAAARRL 480 GLVTRTAPGA PHAAALVEQV AALGSTQHLS SPDNTGVVAA ATATLAAVPL VLAALVLVCL 540 ARCLGGSGRR RVMKAKPE* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01426 | MGT | 2.0e-23 | 327 | 498 | 173 | + glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production [Cellular processes, Toxin production and resistance]. | ||
| PHA03392 | egt | 1.0e-27 | 234 | 494 | 273 | + ecdysteroid UDP-glucosyltransferase; Provisional | ||
| pfam00201 | UDPGT | 8.0e-31 | 166 | 491 | 339 | + UDP-glucoronosyl and UDP-glucosyl transferase. | ||
| COG1819 | COG1819 | 1.0e-38 | 54 | 502 | 452 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| cd03784 | GT1_Gtf_like | 1.0e-39 | 54 | 499 | 451 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ADC91966.1 | 3e-29 | 150 | 550 | 116 | 523 | UDP glucuronosyltransferase 2 family polypeptide b6 isoform 1 [Danio rerio] |
| RefSeq | XP_001701057.1 | 0 | 150 | 558 | 1 | 409 | hypothetical protein CHLREDRAFT_142823 [Chlamydomonas reinhardtii] |
| RefSeq | XP_002717087.1 | 4e-29 | 155 | 551 | 131 | 527 | PREDICTED: UDP glucuronosyltransferase 2 family, polypeptide A3 [Oryctolagus cuniculus] |
| RefSeq | XP_002717087.1 | 8e-17 | 253 | 544 | 616 | 920 | PREDICTED: UDP glucuronosyltransferase 2 family, polypeptide A3 [Oryctolagus cuniculus] |
| RefSeq | XP_002717171.1 | 1e-30 | 155 | 544 | 131 | 513 | PREDICTED: UDP glucuronosyltransferase 2 family, polypeptide A3 [Oryctolagus cuniculus] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2o6l_B | 4e-17 | 313 | 483 | 6 | 167 | A Chain A, Crystal Structure Of The Udp-Glucuronic Acid Binding Domain Of The Human Drug Metabolizing Udp-Glucuronosyltransferase 2b7 |
| PDB | 2o6l_A | 4e-17 | 313 | 483 | 6 | 167 | A Chain A, Crystal Structure Of The Udp-Glucuronic Acid Binding Domain Of The Human Drug Metabolizing Udp-Glucuronosyltransferase 2b7 |
| PDB | 2iyf_B | 0.000000004 | 279 | 498 | 187 | 395 | A Chain A, The Crystal Structure Of Macrolide Glycosyltransferases: A Blueprint For Antibiotic Engineering |
| PDB | 2iyf_A | 0.000000004 | 279 | 498 | 187 | 395 | A Chain A, The Crystal Structure Of Macrolide Glycosyltransferases: A Blueprint For Antibiotic Engineering |
| PDB | 3hbj_A | 0.00000005 | 320 | 466 | 265 | 416 | A Chain A, The Crystal Structure Of Macrolide Glycosyltransferases: A Blueprint For Antibiotic Engineering |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| saponin biosynthesis II | RXN-9000 | EC-2.4.1.17 | glucuronosyltransferase |
| Transmembrane Domains | |||||
|---|---|---|---|---|---|
| Start | End | ||||
| 518 | 540 | ||||
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HS313010 | 216 | 291 | 503 | 0.000000000000002 |
| HO876239 | 216 | 291 | 503 | 0.000000000000002 |
| HO447975 | 240 | 284 | 509 | 0.000000000000002 |
| GD097452 | 222 | 304 | 515 | 0.00000000000009 |
| GW240920 | 178 | 318 | 491 | 0.0000000000001 |
| Orthologous Group | |||||
|---|---|---|---|---|---|
| Species | ID | ||||
| Chlamydomonas reinhardtii | Cre07.g322884.t2.1 | ||||
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
| Phylogeny |
|---|
 |