| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre07.g325050.t1.3 |
| Family | GT47 |
| Protein Properties | Length: 769 Molecular Weight: 86830.3 Isoelectric Point: 7.3203 |
| Chromosome | Chromosome/Scaffold: 7 Start: 1613854 End: 1621517 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 329 | 680 | 0 |
| KRPLIYVYDLDPLYNARLLQYRIVQTWCTHRHYHTGNTSTWSATFYGLEAALHEYLLISEHRTFDPEEADYFYVPFYGACMIYPVAGWADYPWFWTPGGP RVMQVINMIREIVEWIDKQYPFWKRRGGRDHIWLFTHDEGACWAPSVIKDSVWLTHWGRLDPEHTSNTAFVGDNYTHDMVNWRQPEGYIKYIKGHPCYDP QKDLVVPNFKSPPHYVRSPLQSTPSKPRDIFFFFKGDVGKHRLSHYSRGIRQKIYKMAMEQDWANTQKSLIGDGGNVHGDYSDLLSRSLFCLVAPGDGWS PRLEDAVLHGCIPVIIADRVHAVFESVLDIDSFAVRVAEADVPRVMDILRAV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 769 Download |
| MQLQHWLALS ALFLLLVSQL STGLGGRSLA SASASQNGTA PIKQLNLEPL TENSAVESRC 60 ARTTGPWCYN FHTQTPVPWR PAPRGSVDCP GNCNNVGVCN HDTGYCHCRA GWIGEGCTTR 120 RTRPCTNHIR TPESESTEPL SYIGPDKRDL NWTELGFRAS RCFGVCDDDL GACYCDGPMG 180 RVPAPADAPP GTPPIRRGRP LTHAHDQPKT TWDGRPTIGT TDYNKMYGPK GYCNVSEPDW 240 APSMCSPDDL GGKFCDDPVE AFCPGACSGH GFCDLGFCRC NEGYYGHDCA RRKAGLPLQP 300 SDIEQRPWLS FHVREPPAAL EPPPKPTRKR PLIYVYDLDP LYNARLLQYR IVQTWCTHRH 360 YHTGNTSTWS ATFYGLEAAL HEYLLISEHR TFDPEEADYF YVPFYGACMI YPVAGWADYP 420 WFWTPGGPRV MQVINMIREI VEWIDKQYPF WKRRGGRDHI WLFTHDEGAC WAPSVIKDSV 480 WLTHWGRLDP EHTSNTAFVG DNYTHDMVNW RQPEGYIKYI KGHPCYDPQK DLVVPNFKSP 540 PHYVRSPLQS TPSKPRDIFF FFKGDVGKHR LSHYSRGIRQ KIYKMAMEQD WANTQKSLIG 600 DGGNVHGDYS DLLSRSLFCL VAPGDGWSPR LEDAVLHGCI PVIIADRVHA VFESVLDIDS 660 FAVRVAEADV PRVMDILRAV SDIKIRLKQS RLGQVWHRYR YGALPGLRSD LLENMELNER 720 EPLLAEAANN TPRWKVSLPR PFKGDPGVDD AFGTIIQWLH SRIGYTRG* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-55 | 328 | 680 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001691329.1 | 0 | 5 | 767 | 44 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693194.1 | 0 | 76 | 767 | 6 | 661 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693195.1 | 0 | 50 | 767 | 49 | 659 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001697525.1 | 0 | 134 | 698 | 9 | 593 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001700890.1 | 0 | 74 | 768 | 10 | 704 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
