| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre09.g390750.t1.2 |
| Family | GT47 |
| Protein Properties | Length: 827 Molecular Weight: 92239.5 Isoelectric Point: 7.2411 |
| Chromosome | Chromosome/Scaffold: 9 Start: 2552184 End: 2560640 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 353 | 712 | 0 |
| RRPYIYVYDMKSDFGTDLLQYRIEGSHCLYRSFARANQTSFVGYNAYAAEPVLHELFLTSEHRTLDPEEADFFFVPVNVGCLFDVYGWNEIPRWPRGLLG PRTHGATMMQREAARWLNATFPYFARRGGRDHIWLNPHDEGACYVWREVWPGVMLSHWGRMDFPHASNTAYGQDNYSLPLHHDSHPGDWRDHTSLTHPCF DPKKDLVIPAFKQPQLYNKSPFLGAPVRERDVFAFFIGDLRMEPGRDPACRYSRCIRQRLYNISREQHWREAHGVMFGERKDIGGDASYSELLSRSKFCF VLPGDGWSPRWEDAVLHGCVPVVIMDDVQVVFESLIDVSLFSLRIAESDLGRVVEVLKGV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 827 Download |
| MELYKSLGLA LLVLLGLCSQ YALRDKGATL DSRPSSAASG WATFSWPFAA VSVAGPRRTL 60 LQDVENDKHA DEVVHQLIVR LNASRLAPLP VRPQERCVLT RGNWCMQFHL QEPVPRFPPP 120 YYDKPCPNDC NGVGNCNHEY GTCSCPAGWG GADCSQPRKR PCHHMGEGKR DAGWHNLTAW 180 SHTRCAGVCD DDVAMCYCPA DTKYGHREAP PGAKPGTPPE QRGRPLFMCT PGTDKDGKKV 240 LWGGTPYEDM FGPEGWCNAD KPKFTCPCRL DGLLGLTCSE VVEQTCTNQC SGHGECNQGF 300 CKCRAGWYGV DCGLRRRGVL PQPGDQWTTK PWIEPVLTHT VATEDPPLTP VRRRPYIYVY 360 DMKSDFGTDL LQYRIEGSHC LYRSFARANQ TSFVGYNAYA AEPVLHELFL TSEHRTLDPE 420 EADFFFVPVN VGCLFDVYGW NEIPRWPRGL LGPRTHGATM MQREAARWLN ATFPYFARRG 480 GRDHIWLNPH DEGACYVWRE VWPGVMLSHW GRMDFPHASN TAYGQDNYSL PLHHDSHPGD 540 WRDHTSLTHP CFDPKKDLVI PAFKQPQLYN KSPFLGAPVR ERDVFAFFIG DLRMEPGRDP 600 ACRYSRCIRQ RLYNISREQH WREAHGVMFG ERKDIGGDAS YSELLSRSKF CFVLPGDGWS 660 PRWEDAVLHG CVPVVIMDDV QVVFESLIDV SLFSLRIAES DLGRVVEVLK GVSEVRLAEM 720 QAHLAKVWHR YRYMGLRMLD DSARAYLWDY RADAGGKAPR TPGAEFSVSR QDDAFATILQ 780 WLYHRIPDVH GTQQGGSKGA AAAAAGAGAL VGAAAGVGAG VGVAAA* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.009 | 127 | 154 | 28 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam07974 | EGF_2 | 0.004 | 287 | 312 | 28 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 1.0e-39 | 352 | 712 | 362 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001691329.1 | 0 | 94 | 789 | 81 | 814 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001694450.1 | 0 | 62 | 797 | 306 | 854 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698039.1 | 0 | 49 | 791 | 73 | 810 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698117.1 | 0 | 89 | 789 | 65 | 799 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001700890.1 | 0 | 110 | 786 | 9 | 699 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
