Basic Information | |
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Species | Chlamydomonas reinhardtii |
Cazyme ID | Cre09.g414750.t1.3 |
Family | GT47 |
Protein Properties | Length: 745 Molecular Weight: 83857.2 Isoelectric Point: 8.1652 |
Chromosome | Chromosome/Scaffold: 9 Start: 7604838 End: 7611389 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 340 | 656 | 0 |
KRPLVYVYDLEPFYQARILQYRVSPPWCVHRQHLYPGNTTRWTDEWVYAVDTLLHESFLISEHRTFDPEEMINFIREVHTWIDTNYPFWKRRQGRDHIWT WTHDEGACWAPTVLNNSVWLTHWGRMELNHKSHGLPEDNYNKEFKSVNQPEGYLVHIQGHPCYNPQKDLVIPSFKRPEHYHKSGLVGNPTRERDVSFYFK GDVGKGRFPPYSRGVRQGIYKLAKEGDWATKHKFLIGGRSDVPGDYSDMLSRAIFCLVAAGDGWSGRMEDAMLHGCIPVIIIDEVHVVFESLLDVDTFSI RIAQKDVPRILEILQAV |
Full Sequence |
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Protein Sequence Length: 745 Download |
MSARNRARWR HFFGLLAALC LTNVVLHASG AYGQTAGLAL DRNGSSQGRL SRERKFALTQ 60 TTPAAVRCTA AKGKWCEDFL LQEEVLWKPA PRGSKECPDN CNNVGRCNYD TGYCDCAAGW 120 TGVGCKTPQK RPCTSTWREP EDPSKIPTSH IGPDKRDLNW TVWSNIHSRC GGICDDDLAI 180 CYCDGQGPNQ FGRIPAPPGS PPGTPPIRVG RPLVTEYMAP NETWDGKWAF GRQPYSNVYG 240 PQGYCNVSKP VWAAVCSMDA LAGPTCDEPL ESFCPGACSG HGRCYLGYCY CDEGYYGHDC 300 ARRKAGLPLL PSSIPTTPWL ASVVREPPAA QEPPPVPTRK RPLVYVYDLE PFYQARILQY 360 RVSPPWCVHR QHLYPGNTTR WTDEWVYAVD TLLHESFLIS EHRTFDPEEM INFIREVHTW 420 IDTNYPFWKR RQGRDHIWTW THDEGACWAP TVLNNSVWLT HWGRMELNHK SHGLPEDNYN 480 KEFKSVNQPE GYLVHIQGHP CYNPQKDLVI PSFKRPEHYH KSGLVGNPTR ERDVSFYFKG 540 DVGKGRFPPY SRGVRQGIYK LAKEGDWATK HKFLIGGRSD VPGDYSDMLS RAIFCLVAAG 600 DGWSGRMEDA MLHGCIPVII IDEVHVVFES LLDVDTFSIR IAQKDVPRIL EILQAVPERK 660 IRSMQAHLGH VWHRFRYTSL PGLANELVRV TEANKKALGP GAATANATLP SRVPLPRAFK 720 GDPSVDDAFG TILQWLYSRI PYTR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-40 | 339 | 656 | 339 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001691329.1 | 0 | 67 | 744 | 83 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001693194.1 | 0 | 85 | 744 | 7 | 661 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001693195.1 | 0 | 53 | 744 | 44 | 659 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001697525.1 | 0 | 147 | 674 | 14 | 593 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001700890.1 | 0 | 79 | 744 | 7 | 703 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |