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Basic Information | |
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Species | Chlamydomonas reinhardtii |
Cazyme ID | Cre10.g430100.t1.3 |
Family | GT47 |
Protein Properties | Length: 585 Molecular Weight: 66282.6 Isoelectric Point: 8.572 |
Chromosome | Chromosome/Scaffold: 10 Start: 1678406 End: 1683991 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 151 | 444 | 1.2e-39 |
HGVKIYVYELPPVANTWTYIARIDRPLVQVLLQRMLSSGVRTTDGDSADYYFIPLLMRTRTHTVNHLAAVVHYVRKHWPWWDRTGGGHRHLLVAPGDIGR RILTPELLHMTENCTFLTHWGLHRNHSGGNWLASHRPGKDIVVPPLTPPDEPIVYSPLHATLKKNRKSRLGELFFAGRICGDNQKPTDGKCSEKRQDYSA GTRQQVAHHHWNRPNWTITTHTPAYAEALSTHIFCLSPTGGGYGRRSVQSLLMGCIPVTVTDHVHQPFEPEVDWARFSVPVREDDIAQLHHVLT |
Full Sequence |
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Protein Sequence Length: 585 Download |
MKFVHAQKDA QSTTQQQSRR IPLCSVLCLL LATCSRAEKR NATCLTDQCF EYGTCNPETD 60 RCECPLGRHG LDCSIPIPDP EPQCKEHSHN LVTCTSFTKT LCLNSCNGQG WCAGGFCHCK 120 PGFYGADCSL STSPDGRPVL LAGQGYMPRQ HGVKIYVYEL PPVANTWTYI ARIDRPLVQV 180 LLQRMLSSGV RTTDGDSADY YFIPLLMRTR THTVNHLAAV VHYVRKHWPW WDRTGGGHRH 240 LLVAPGDIGR RILTPELLHM TENCTFLTHW GLHRNHSGGN WLASHRPGKD IVVPPLTPPD 300 EPIVYSPLHA TLKKNRKSRL GELFFAGRIC GDNQKPTDGK CSEKRQDYSA GTRQQVAHHH 360 WNRPNWTITT HTPAYAEALS THIFCLSPTG GGYGRRSVQS LLMGCIPVTV TDHVHQPFEP 420 EVDWARFSVP VREDDIAQLH HVLTGLRASP HTLAQMQVRL RCAAQHMYYS STFGEIMGED 480 GRFDAFETLM EVLRMRKERP ELHPRDYEAQ DKRFHDFIHC RSKPTGGRVQ LCTQNRLVKS 540 NNITHCRESY DAVPMRWMRM FYSWPGGAVC GRNRDVGRCP RSWL* 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-33 | 149 | 443 | 312 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001693540.1 | 0 | 49 | 511 | 9 | 487 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001702517.1 | 0 | 37 | 495 | 3 | 479 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001702686.1 | 0 | 31 | 567 | 60 | 600 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001703124.1 | 0 | 54 | 533 | 3 | 484 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001703125.1 | 0 | 48 | 524 | 70 | 511 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |