| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre11.g483400.t1.3 |
| Family | GT47 |
| Protein Properties | Length: 754 Molecular Weight: 84118.5 Isoelectric Point: 7.4496 |
| Chromosome | Chromosome/Scaffold: 11 Start: 3794387 End: 3801990 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 242 | 535 | 1.5e-35 |
| RGPKIYVYEFPPQYHVWSLLWLDRPLNIILWERLMSLGLRTVNPEEADYFFLPGCGRGCNKWDQKFKYIMEHYAKYWNRRNGRDHLMTHAGDWGRCEKAW GPDSAPFIANLTMLNHWGITVDRSQETEHDLFNACHIPDQDIQVPVLCGDLYPQFEHNVWHPKRRAHPVNKTVLASVAGSICGWNSAEEPPCKNKYYSFG VRAALWTTLRDKPGFHIAKRVPVLGQSMAESEFCFAPTGAGHGKRQVVSVTLGCMPVIISDHVAQPFEPFLDWNDFGVWIAEADLPDVEAILRG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 754 Download |
| MARPRPLCSA FLALVLTLAC VHASFQDDFD IVWGISHGVW GSGRSRIGRR LLTRDLSMDE 60 IFRYWQKMYG KWPTDVYETH LTDYRNHVAR SGREFGIPRN DQEFLDLYYY LRNRTEVPRA 120 VGWTPERERC APGCYLHGTC NQELGRCDCP RGRQGPDCSE PLATSCREFC QHDGQCHRVI 180 REWCINECND RGSCVGGFCH CWPGYFGTDC SLSVDYEGKE PNSNGPNTTV LLAGQGYRPN 240 PRGPKIYVYE FPPQYHVWSL LWLDRPLNII LWERLMSLGL RTVNPEEADY FFLPGCGRGC 300 NKWDQKFKYI MEHYAKYWNR RNGRDHLMTH AGDWGRCEKA WGPDSAPFIA NLTMLNHWGI 360 TVDRSQETEH DLFNACHIPD QDIQVPVLCG DLYPQFEHNV WHPKRRAHPV NKTVLASVAG 420 SICGWNSAEE PPCKNKYYSF GVRAALWTTL RDKPGFHIAK RVPVLGQSMA ESEFCFAPTG 480 AGHGKRQVVS VTLGCMPVII SDHVAQPFEP FLDWNDFGVW IAEADLPDVE AILRGFTPQQ 540 KAAKMKKLYC AARHVAYTTV FGGLFDGDTG EYDAIATIFN ILRVRLRHPG VPDHELMKMD 600 QDFADFMACK PGSPRASGLV AGAAAPPAPP LPNAASNARY KDSIDAKAFP HRTVTTAAWI 660 KAVAGTGAAT TQQVQPSTDT AAMIPGPLCA FNGHWVAYAS FDTPGNPSAE LGNAHRAQGQ 720 CMPKNANRPG NFPPGGSITC PPIGPITECA VLV* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 0.007 | 186 | 210 | 27 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam07974 | EGF_2 | 0.003 | 134 | 158 | 25 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 8.0e-34 | 241 | 536 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001693540.1 | 0 | 129 | 609 | 4 | 496 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001697348.1 | 0 | 89 | 723 | 27 | 618 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 130 | 639 | 73 | 583 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 139 | 610 | 3 | 472 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703125.1 | 0 | 121 | 623 | 58 | 527 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4k0v_A | 0.007 | 119 | 212 | 190 | 291 | A Chain A, Structural Basis For Angiopoietin-1 Mediated Signaling Initiation |
