| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre12.g502450.t1.3 |
| Family | GT47 |
| Protein Properties | Length: 647 Molecular Weight: 72182 Isoelectric Point: 7.4517 |
| Chromosome | Chromosome/Scaffold: 12 Start: 2830337 End: 2834918 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 156 | 457 | 1.1e-33 |
| KRPLIYVYDIPHKLSSWHNVMRADRGLAWVFWQRLLGAGVLTTNGDEADWFYIPVKLRSTSDGYSLKDAVSYIRSHWPWFERYGGNRHFVLHSGDTGRGE VTGAIREDATLANITWLHHWGLTEDYPSSGWRKAHRVGKDVVVPIYLGVRKSAGLLPLSGLHPLAPRIPRNGTFLFSGRICGDHSLPDPEKPWPHCATRR SPGYSQGARQLVHFHHSQRPGYKVMVKNKEYQVDLINYKWCLAPSGGGHGHRQVLVAAMGCLPVVVSDLVMQPFEPEMDWSAFSLRVEQKDVPTLHEAIE AV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 647 Download |
| MNHPVHRLAA AWQLRLVSIL LVALVASKGK VDEEALEQQA PAYTAPTPGV CSERCYDIAT 60 CNEELGGRCD CPKTLSGSEC HQKATKESLQ TYGQSTVKEA KDPLPCLNDC NGRGTCVYGA 120 CVCTRGNFTS DCSVSLGPDT QQPVVLAGSG YEARRKRPLI YVYDIPHKLS SWHNVMRADR 180 GLAWVFWQRL LGAGVLTTNG DEADWFYIPV KLRSTSDGYS LKDAVSYIRS HWPWFERYGG 240 NRHFVLHSGD TGRGEVTGAI REDATLANIT WLHHWGLTED YPSSGWRKAH RVGKDVVVPI 300 YLGVRKSAGL LPLSGLHPLA PRIPRNGTFL FSGRICGDHS LPDPEKPWPH CATRRSPGYS 360 QGARQLVHFH HSQRPGYKVM VKNKEYQVDL INYKWCLAPS GGGHGHRQVL VAAMGCLPVV 420 VSDLVMQPFE PEMDWSAFSL RVEQKDVPTL HEAIEAVDEH KYEEMQDALR CAAQHMIFST 480 MSGAFMQEDG KWDAFGFVLE ILRMQQGHPG LHPSKYAEVD EQYRDFLNCG DPDGMASYGR 540 KLRETQLAKY PTAPSLSKDP EKPMDWSDVY RKATAGFKKL VDAHRLPAEG SEPEPPLPLC 600 SMSLWDPEQV RCSKVGHRER VHHSYIPGGA ACVMHKNLAE CPRLWE* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-24 | 154 | 457 | 321 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001690974.1 | 0 | 256 | 646 | 14 | 341 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693540.1 | 0 | 51 | 529 | 5 | 496 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693783.1 | 0 | 51 | 646 | 42 | 611 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 50 | 533 | 72 | 559 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 58 | 532 | 1 | 474 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
