| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre12.g502500.t1.2 |
| Family | GT47 |
| Protein Properties | Length: 644 Molecular Weight: 72213 Isoelectric Point: 6.7135 |
| Chromosome | Chromosome/Scaffold: 12 Start: 2825587 End: 2830288 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 153 | 454 | 1.7e-31 |
| KRPLIYVYDIPHKLSSWYNVLKIDRGLPWVFWERLLGSGALTANGDEADWFFIPVKLRSTTDGYKLQEAVKYIRSKWPWFDKYDGNRHFVLHSGDTGRGE VTGAIREDATLANITWLHHWGLTEDYPSSGWRKAHRVGKDIVVPIYFGAKQGHAFVPMSGLHPLAPRIPRNGTFLFSGRICGDHSLPDPEKPWPHCATNR SHGYSQGARQWVHFHHSQRPGYKIVVSNKEYPVDLLNYKWCLAPSGGGHGHRQALVAVMGCLPVVVSDLVMQPFEPEMDWSAFSLRVEQKDVPTMHEAIE AV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 644 Download |
| MSREEGSWRC LLPILVLTLV TCSAAVEEED AAESQSALGY ATIKPGVCSE ECYTVATCNE 60 ELGGRCDCPK TLSGKDCHRK ATKGNLHAFG QDSARELRAP FPCLNDCNGR GKCVYGACVC 120 TRGNFTSDCS VSLDPDTQQP VVLAGSGYEA RRKRPLIYVY DIPHKLSSWY NVLKIDRGLP 180 WVFWERLLGS GALTANGDEA DWFFIPVKLR STTDGYKLQE AVKYIRSKWP WFDKYDGNRH 240 FVLHSGDTGR GEVTGAIRED ATLANITWLH HWGLTEDYPS SGWRKAHRVG KDIVVPIYFG 300 AKQGHAFVPM SGLHPLAPRI PRNGTFLFSG RICGDHSLPD PEKPWPHCAT NRSHGYSQGA 360 RQWVHFHHSQ RPGYKIVVSN KEYPVDLLNY KWCLAPSGGG HGHRQALVAV MGCLPVVVSD 420 LVMQPFEPEM DWSAFSLRVE QKDVPTMHEA IEAVDEQKYE EMQDALRCAA QHMIFSTMSG 480 AFMQEDGKWD AFEFVLEILR MQQGHPGLHP SKYAEVDEQY RDFLNCGDPD GMASYGRKLR 540 EAQLAKYPTA PSLSKDPEEP MDWSDLYKSS MNGLKKLLEL HRLPAEGSEP EPPLPLCSMS 600 LWDPEQVRCS KVGHRERVHH PYIPGGAACV MHKNLAECPR MWE* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-25 | 151 | 454 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001690974.1 | 0 | 253 | 643 | 14 | 341 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693540.1 | 0 | 48 | 526 | 5 | 496 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693783.1 | 0 | 48 | 643 | 42 | 611 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 26 | 530 | 49 | 559 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 55 | 529 | 1 | 474 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
