| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre12.g527950.t1.3 |
| Family | GT28 |
| Protein Properties | Length: 489 Molecular Weight: 48915.4 Isoelectric Point: 9.686 |
| Chromosome | Chromosome/Scaffold: 12 Start: 5210917 End: 5214712 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT28 | 267 | 419 | 1.4e-36 |
| LVVLGGSKGCCYLNQATHNALPQLANVSGLQVLWQTGIRQHVAYSGGQAATMSNVRCVPHISDVGSALAAADLVLSRAGAASVAELGAVGAPCLLVPSPA VDEERQTANAHVLVDAGLAELVPQLHVDEHGISGRLLPLLSPEGGKRLAAMKG | |||
| Full Sequence |
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| Protein Sequence Length: 489 Download |
| MGISPKKVAL GAVATAAVGY GGFRATLHVR RQCHAAPMIA LAGCHVYSGL ALAEALRLQG 60 VESVFLGTRG VIGSQYRAIA AHGFNMHEVP YVELVRPLKR MANVWGALRF PFCVLSSACA 120 LVGAAPDVVV GIGGSMSVPA CLAAIALGIP LLVYEPNAAA GAANASIHRL ARQTLLAFPA 180 AAAGLKFPER CTVIGPAVRP GVLTSAGVNK PDPGAGTTTG KVVTRCGGGC DAKSRAAAEK 240 RRAQAREALG LKGRSGSGAG SGSERLLVVL GGSKGCCYLN QATHNALPQL ANVSGLQVLW 300 QTGIRQHVAY SGGQAATMSN VRCVPHISDV GSALAAADLV LSRAGAASVA ELGAVGAPCL 360 LVPSPAVDEE RQTANAHVLV DAGLAELVPQ LHVDEHGISG RLLPLLSPEG GKRLAAMKGK 420 CCSSCKVGSS SSSSGSSSKT GGASTAAGSQ AAAVPSGGGA GAAALVHFPT GWEALDTGCR 480 AILGHVRR* 540 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0707 | MurG | 1.0e-10 | 38 | 206 | 173 | + UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
| COG0707 | MurG | 9.0e-21 | 268 | 418 | 155 | + UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
| TIGR01133 | murG | 6.0e-38 | 38 | 390 | 362 | + undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]. | ||
| PRK00726 | murG | 2.0e-47 | 37 | 417 | 393 | + undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional | ||
| cd03785 | GT1_MurG | 4.0e-54 | 38 | 418 | 392 | + MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001696869.1 | 0 | 1 | 429 | 1 | 429 | hypothetical protein CHLREDRAFT_192581 [Chlamydomonas reinhardtii] |
| RefSeq | XP_002509362.1 | 6e-32 | 43 | 385 | 21 | 325 | glycosyltransferase family 28 protein [Micromonas sp. RCC299] |
| RefSeq | YP_360888.1 | 7e-31 | 43 | 422 | 11 | 347 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Carboxydothermus hydrogenoformans Z-2901] |
| RefSeq | YP_592704.1 | 8e-33 | 43 | 406 | 11 | 319 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Candidatus Koribacter versatilis Ellin345] |
| RefSeq | ZP_01908543.1 | 3e-31 | 43 | 432 | 33 | 378 | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase [Plesiocystis pacifica SIR-1] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nlm_B | 4e-25 | 43 | 394 | 17 | 313 | A Chain A, Crystal Structure Of Phosphatidylinositol Mannosyltransferase (Pima) From Mycobacterium Smegmatis In Complex With Gdp-Man |
| PDB | 1nlm_A | 4e-25 | 43 | 394 | 17 | 313 | A Chain A, Crystal Structure Of Phosphatidylinositol Mannosyltransferase (Pima) From Mycobacterium Smegmatis In Complex With Gdp-Man |
| PDB | 1f0k_B | 4e-25 | 43 | 394 | 17 | 313 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| PDB | 1f0k_A | 4e-25 | 43 | 394 | 17 | 313 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| PDB | 3s2u_A | 8e-24 | 43 | 390 | 13 | 306 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| BI718968 | 107 | 279 | 385 | 0 |
| BI725925 | 98 | 279 | 376 | 1.96182e-44 |
| ES821435 | 388 | 42 | 410 | 1e-23 |
| BI725925 | 48 | 277 | 323 | 0.003 |
| BI718968 | 48 | 277 | 323 | 0.008 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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