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Basic Information | |
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Species | Chlamydomonas reinhardtii |
Cazyme ID | Cre12.g561050.t1.3 |
Family | GT47 |
Protein Properties | Length: 708 Molecular Weight: 78284 Isoelectric Point: 7.863 |
Chromosome | Chromosome/Scaffold: 12 Start: 6873368 End: 6878199 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 175 | 476 | 0 |
KRPWVYVYELPPELSAWYNHRRLDRPTHMLFAQRLLSSGARIADGDQADYYYIPVRQRSAPESSLLVDAIKHIRQHYPWWNRTQGHKHFVIQTGDWGRAE MDPNLLQLTENMTWLTHWGLTTDRHDKILRWVPSYRPEKDVVVPVFISPGHFVKFSMIHTPLNPANKAKPRDKARFFFAGRICFNSKYPTKATWPHCDGD HWAYSAGVREKVFVSHWNRSGYHVARSEKRYGQYLARSLYCLAPPGAGHGQRQIQALFMGCVPVTIADGVAEPFEPAVNWTDWGVRVAEADVPQMHTLLD DI |
Full Sequence |
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Protein Sequence Length: 708 Download |
MPGRRPAPLL LVALVWALGC QLRVNAFFFR SKPAPKQHPE HPAPALARAP APAAAVGVPF 60 TPGVSRCPAN CSRFGSCNEE TGSCDCLRNR MGPDCGRKLM RPGMLQRCQD MGYKDVKECL 120 AKDQLCVNAC NKLGRCVAGV CHCKKGYYGI DCALSMGQDG QPVLLAGKGY ATRAKRPWVY 180 VYELPPELSA WYNHRRLDRP THMLFAQRLL SSGARIADGD QADYYYIPVR QRSAPESSLL 240 VDAIKHIRQH YPWWNRTQGH KHFVIQTGDW GRAEMDPNLL QLTENMTWLT HWGLTTDRHD 300 KILRWVPSYR PEKDVVVPVF ISPGHFVKFS MIHTPLNPAN KAKPRDKARF FFAGRICFNS 360 KYPTKATWPH CDGDHWAYSA GVREKVFVSH WNRSGYHVAR SEKRYGQYLA RSLYCLAPPG 420 AGHGQRQIQA LFMGCVPVTI ADGVAEPFEP AVNWTDWGVR VAEADVPQMH TLLDDIGPEQ 480 LAVKQARMRC AAQHMLYSSI TGGVFGEDGA FDAFETTLEV MRVRAEHPDA RQEDFRKLDA 540 AFDAFMDCRE PPGPQPAFRR LSGLLPDAQV LAELQAEEAA EAAAEAAAEA AEAARSSKGL 600 GRDGEDEEGD EEQDEEDGGW AVEDGKVGER DQEAGTAAVL SAKARPPAAP GTPPLLALCS 660 HAYSDIHNHD RSCYYVMRGG GYMGVPGGAI CARGFKSRLA QCPRLWA* 720 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-34 | 179 | 476 | 319 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001693540.1 | 0 | 66 | 539 | 4 | 487 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001693783.1 | 0 | 67 | 484 | 42 | 470 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001702686.1 | 0 | 65 | 580 | 71 | 587 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001703124.1 | 0 | 84 | 562 | 10 | 481 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
RefSeq | XP_001703125.1 | 0 | 1 | 569 | 1 | 528 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |