| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre14.g619854.t1.2 |
| Family | GT47 |
| Protein Properties | Length: 1021 Molecular Weight: 109819 Isoelectric Point: 5.9696 |
| Chromosome | Chromosome/Scaffold: 14 Start: 1779333 End: 1791118 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 539 | 842 | 0 |
| HKLRIYMYELPWQAAFPGEFNDADSYRDPIYIAYEQFLTRFLNDSTVRTENPYEATLFYVPLLAYWYGANVGPGHLQVEAVLRRHVAATWPFWNRTGGRD HFFFMDNDRGACHLTRRLQDRPIKLVHFGLQAARRPRSSITNNADYACVQVKRDLVVPPFVQFPRTAADYYKRLAAAGGADAERTTLLFFAGSLRTDDRE YSGGARQAVAAMLAALGDRRPADVEFVEGWVGNYGKHYRAAHFCLAPYGHGWGIRLSEAVSWGCIPVLVQDMVYQPFEDFIPYEEFSVRLPHHDIPRLLD ILRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1021 Download |
| MRGWHTRAST TFCSSSLLVA IIAHVAFIAY VLETVDTSAT PAVVQRLLPC PAGCEKRGNC 60 DAERGVCQCP WGWDGPACEH DRMAACKSTS RDPGFCGSTV PKNCECYREC YRLYCPARSP 120 WTGSDLEDVC THGAGRGLYR AHCYLYNSDS GHPANDSVYP ADLSATTWFR HIPEVEGGHR 180 YRNSLKAPEL AGAPGKWEGS LLRPAALDEC ADRCSEGQGV CVVPNPDSWE WSFERLQDTR 240 KDDDDQAEAE GGKGEEGKGE AGAVTWDDAL GEAHGEEEEK GLKEPRPRCW CRLGFKGRTC 300 AELNPESCWF SPNCSGAGTC RSGFCHCRPG RWGLGCARTA AYQPALIAAA AAAAARAAAP 360 AVTAGAGATG AAVAAGAAGP APARAAGAAA ARAAAAARAA AAGVGAVRRP AAGAGAGASA 420 GAGAGASAGA GAGASAGAGA GASAGAGAGA SRPGKTSGKR SGKRSGNRSG KRQKMEEEED 480 DDEEQQQDYA SEQEQDYAAE QEQDYGADDY DVGESEEAAG GVEPQPSELA ELPDMRSMHK 540 LRIYMYELPW QAAFPGEFND ADSYRDPIYI AYEQFLTRFL NDSTVRTENP YEATLFYVPL 600 LAYWYGANVG PGHLQVEAVL RRHVAATWPF WNRTGGRDHF FFMDNDRGAC HLTRRLQDRP 660 IKLVHFGLQA ARRPRSSITN NADYACVQVK RDLVVPPFVQ FPRTAADYYK RLAAAGGADA 720 ERTTLLFFAG SLRTDDREYS GGARQAVAAM LAALGDRRPA DVEFVEGWVG NYGKHYRAAH 780 FCLAPYGHGW GIRLSEAVSW GCIPVLVQDM VYQPFEDFIP YEEFSVRLPH HDIPRLLDIL 840 RSYTPEQRDA LRLGLVRWHT AFLWDWERGG RAYELTLKGL ERRAYNLHTD MWRRRRRGRR 900 RRLLETGARE AEAEAEAASG GGPCARMEED EGEGGSESVL CGSSAGIGLS RRLLGDRRLA 960 GDGVHAGGGG SEPRQNRERK EPGRLRQGGG SEAGGLELED AAPLGEASGG RGQDDAYELV 1020 * 1080 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-40 | 537 | 843 | 314 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001690303.1 | 0 | 1 | 229 | 1 | 233 | topoisomerase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001690303.1 | 0 | 547 | 878 | 239 | 484 | topoisomerase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693329.1 | 4e-27 | 68 | 362 | 1 | 233 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693329.1 | 0 | 533 | 892 | 235 | 599 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693348.1 | 0 | 545 | 892 | 1 | 347 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
