| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre14.g622050.t1.3 |
| Family | GT47 |
| Protein Properties | Length: 755 Molecular Weight: 80652.1 Isoelectric Point: 7.0862 |
| Chromosome | Chromosome/Scaffold: 14 Start: 2064366 End: 2070707 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 198 | 542 | 3.9e-31 |
| PPRVYVYDLPHKWTSWFHPKKLDRATHWALWERLLSSGVMTADGEQADWYFLPLKLRSTGDGPKLLQALAYVRKHWPWFDRLQGHRHFVLHTGDSGRGEV QAAVRAATANMTWLHHFGLIRDFPYSGWKAGHRPGKDVVVPILFGERQGAAFLPLSPLHPRSPPGQLLRRGLAGDGSSSGTGGSSSSSGGSSNIGGSSGS GGSSSSGGSSSGAHGGELLFVGRICGDGSAPVPGKAWPHCATQRSKGYSQGARQWVHYHHHNRTGYKVTTSSKTYPLDFMSYRWCLAPSGGGHGHRQTLA AAMGCLPVVVSDGVLQPFEPEMDWAAFALRVAHPDVPGMHQVLGA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 755 Download |
| MPHTCWRHLL AYVLLALGSS LAWVLPEQED VLTDADHAAL LSLGEHQLHS GRQQRAAALV 60 AAWRRVQQEE GEEGTGDADT TTTGGRKVCS ADCYKWATCN EELGRCDCPK HRAGESCERN 120 ASAAAMRYFV QSAAREAEQP LTCLSGCSGR GACVLGGCVC ERGFWGSDCS LSWAADGRGL 180 VLLAAGGPRP APPPRAAPPR VYVYDLPHKW TSWFHPKKLD RATHWALWER LLSSGVMTAD 240 GEQADWYFLP LKLRSTGDGP KLLQALAYVR KHWPWFDRLQ GHRHFVLHTG DSGRGEVQAA 300 VRAATANMTW LHHFGLIRDF PYSGWKAGHR PGKDVVVPIL FGERQGAAFL PLSPLHPRSP 360 PGQLLRRGLA GDGSSSGTGG SSSSSGGSSN IGGSSGSGGS SSSGGSSSGA HGGELLFVGR 420 ICGDGSAPVP GKAWPHCATQ RSKGYSQGAR QWVHYHHHNR TGYKVTTSSK TYPLDFMSYR 480 WCLAPSGGGH GHRQTLAAAM GCLPVVVSDG VLQPFEPEMD WAAFALRVAH PDVPGMHQVL 540 GAVDAAAYAG LQAAVRCAAE HLLYSSISGA VAGESGRWDA FETILEVLRM QQTYPGLDPA 600 RYADTDERFR TFINCGARSM REYGEAVRQA AAVEYGGAAA LVEKVYGKEG LAGFSWDTVY 660 DKGLDLLLRA AEAEVQGQEE GEAEEAEEQW RRLRVGGGQG DEGVGVGVGG QRLCSASRWD 720 PASRRCGSRR DAAPQGGGAG EGGWDAVDKA LDEA* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-7 | 471 | 543 | 74 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| pfam03016 | Exostosin | 4.0e-8 | 201 | 341 | 154 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001690974.1 | 0 | 297 | 612 | 14 | 281 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001693540.1 | 0 | 89 | 606 | 5 | 487 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702517.1 | 0 | 88 | 590 | 9 | 479 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001702686.1 | 0 | 64 | 615 | 36 | 553 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001703124.1 | 0 | 97 | 615 | 2 | 471 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
