| Basic Information | |
|---|---|
| Species | Chlamydomonas reinhardtii |
| Cazyme ID | Cre17.g721750.t1.3 |
| Family | GT47 |
| Protein Properties | Length: 825 Molecular Weight: 93015.5 Isoelectric Point: 7.2978 |
| Chromosome | Chromosome/Scaffold: 17 Start: 3154966 End: 3164817 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 378 | 734 | 0 |
| RPLIYIYDLTDYTTKFLQLRLGADACMWRRYSQDNSSFLLSMTYSVEAYLHETLLQSEHRTFDPDEADFFYVPVYVTCYMWPILGWADGPWWYAPLAHTR TMHVSNMLSEVHAHISSTFPWWNRRGGRDHIWLMAADEGACYMPTAIYNTSIILTHWGRMDLEHQSNTAYQQDNYNMAMPGEFKAWPGMDWQSRMRGHPC YDPRKDLVIPAFKSVDHFRDSPLLGGAPLVRDLLCYFRGDIGQARFPQYSRGLRQKLFHLWHKNDWAAKHKIYIGNGEMVRGPYSEHLLRSRFCLVLPGD GWSPRAEDAVLHGCIPVVIMDNVHAVFESILDWESFSIRIREDDAALEALPQLLEAV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 825 Download |
| MDAACTRSLG LVLLLLVLSD ASWLPWTSEQ ELAASSSSSR RRTLLQIGFQ VPKISIQLPL 60 RQYLNGSNSG AAGAGSNRTD HSELAGAAGG EARRDEGDLR RRCAVAKGSW CGAYLRQDMV 120 PYKTAPRGDK ECPNACSGWG NCNHDTGLCE CPAGRAGPAC EREVKRPCTN RFRHPHEVNV 180 NESVGHIGPD KHDLDIQAPG WIASRCSGYC IDHLALCTCG RDSKYRHIPA PAGSPPWTPP 240 VQWGRPMTDG CMIGVDKDGN RIDWGRPHIK DSDLYGPEAW CNKDNPISHQ CGCVWDGNGW 300 PCDGSQQYEP FCPNQCTGHG DCHMGWCRCH PGWYGTDCSR KKAGMELDEG HLSRPWIKRT 360 VDVPPASLRT PPLPTRPRPL IYIYDLTDYT TKFLQLRLGA DACMWRRYSQ DNSSFLLSMT 420 YSVEAYLHET LLQSEHRTFD PDEADFFYVP VYVTCYMWPI LGWADGPWWY APLAHTRTMH 480 VSNMLSEVHA HISSTFPWWN RRGGRDHIWL MAADEGACYM PTAIYNTSII LTHWGRMDLE 540 HQSNTAYQQD NYNMAMPGEF KAWPGMDWQS RMRGHPCYDP RKDLVIPAFK SVDHFRDSPL 600 LGGAPLVRDL LCYFRGDIGQ ARFPQYSRGL RQKLFHLWHK NDWAAKHKIY IGNGEMVRGP 660 YSEHLLRSRF CLVLPGDGWS PRAEDAVLHG CIPVVIMDNV HAVFESILDW ESFSIRIRED 720 DAALEALPQL LEAVPPERVA KMQRNLARVW HRFAYATGPV MAAHLRRIAA TSATAMPEME 780 AAQAVATLTP RDTPFRPLPA YPVSDDAFHT ILQWLHHRIN ETRA* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-44 | 381 | 717 | 339 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001691329.1 | 0 | 58 | 823 | 37 | 815 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001697121.1 | 0 | 1 | 824 | 1 | 802 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698039.1 | 0 | 96 | 824 | 106 | 810 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698117.1 | 0 | 33 | 823 | 18 | 800 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| RefSeq | XP_001698801.1 | 0 | 103 | 823 | 133 | 942 | exostosin-like glycosyltransferase [Chlamydomonas reinhardtii] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2ygo_A | 0.007 | 117 | 161 | 138 | 179 | A Chain A, Wif Domain-Egf-Like Domain 1 Of Human Wnt Inhibitory Factor 1 In Complex With 1,2-Dipalmitoylphosphatidylcholine |
