Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.056260.1 |
Family | GT47 |
Protein Properties | Length: 375 Molecular Weight: 43733.9 Isoelectric Point: 9.1636 |
Chromosome | Chromosome/Scaffold: 00602 Start: 417166 End: 420118 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 1 | 307 | 0 |
MYDLPRRFNVGILNRRNLDQTPVTASTWPPWPRNSGLKRQHSVEYWMMGSLLHEATGDGRDAVRVMDPENADAFFVPFFSSLSFNSHGRNMTDPATEVDH QLQIDLMKFLSESKYWQRSKGRDHVIPMTHPNAFRFLRNQVNASIQIVVDFGRYPKTMSNLGKDVVAPYVHVVSSFIDDNPPDPFESRPTLLFFQGKTFR KDDGIIRVKLAKILDGYDDVHYERSAATEKSIKTSSQGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDQIELPYEDEIDYSQFTLFFSFEEALQP GYMVEKL |
Full Sequence |
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Protein Sequence Length: 375 Download |
MYDLPRRFNV GILNRRNLDQ TPVTASTWPP WPRNSGLKRQ HSVEYWMMGS LLHEATGDGR 60 DAVRVMDPEN ADAFFVPFFS SLSFNSHGRN MTDPATEVDH QLQIDLMKFL SESKYWQRSK 120 GRDHVIPMTH PNAFRFLRNQ VNASIQIVVD FGRYPKTMSN LGKDVVAPYV HVVSSFIDDN 180 PPDPFESRPT LLFFQGKTFR KDDGIIRVKL AKILDGYDDV HYERSAATEK SIKTSSQGMR 240 SSKFCLHPAG DTPSSCRLFD AIVSHCVPVI VSDQIELPYE DEIDYSQFTL FFSFEEALQP 300 GYMVEKLREF PKERWIEMWK QLKEISRHYE FQYPPKKEDA VNMLWRQVKH KLPAVKLAVH 360 RSRRLKVPDW WQRR* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 1.0e-63 | 1 | 310 | 318 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_176908.2 | 0 | 1 | 371 | 57 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 1 | 374 | 57 | 429 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 1 | 371 | 6 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002456855.1 | 0 | 1 | 371 | 65 | 431 | hypothetical protein SORBIDRAFT_03g044100 [Sorghum bicolor] |
RefSeq | XP_002512333.1 | 0 | 1 | 374 | 60 | 434 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DY266782 | 309 | 1 | 309 | 0 |
FC916665 | 305 | 1 | 305 | 0 |
EC955869 | 281 | 69 | 349 | 0 |
DY292809 | 294 | 1 | 294 | 0 |
DT749776 | 259 | 113 | 371 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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