| Basic Information | |
|---|---|
| Species | Cucumis sativus |
| Cazyme ID | Cucsa.078450.2 |
| Family | GT1 |
| Protein Properties | Length: 414 Molecular Weight: 46613.8 Isoelectric Point: 7.8334 |
| Chromosome | Chromosome/Scaffold: 00793 Start: 804509 End: 811271 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT1 | 78 | 384 | 0 |
| ADAIIANRTAYGHTHVAEGLKLPLHIFFTMPWTPTSEFPHPLSRVKQQAGYRLSYQIVDSLIWLGLRDIINDFRKKKLQIRPVTYLSGSQFSESDVPHVY LWSPYIVPKPKDWGPKIDVVGYCFLDLSSNYEPPESLVKWLEAGDKPVYIGFGSLPVQDPEKMTQIIIQALETTKQRGIINEGWGGLGKSAEPKDFLYLL DNCPHDWLFPKCKAVVHHGGAGTTAAGLKAACPTTVVPFFGDQPFWGERVHDKGVGPPPIPVDEFSLQRLVNAINYMLDPKVKERAVLLAKVLENEDGVE GAVRAFF | |||
| Full Sequence |
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| Protein Sequence Length: 414 Download |
| MPLQMKFFKE SRVTRTGQKL LEYAAWDYGH RVRLATHPNF KEFVLLAGLE FYPLGGDPKE 60 LAASCKDPDM DTGIPFEADA IIANRTAYGH THVAEGLKLP LHIFFTMPWT PTSEFPHPLS 120 RVKQQAGYRL SYQIVDSLIW LGLRDIINDF RKKKLQIRPV TYLSGSQFSE SDVPHVYLWS 180 PYIVPKPKDW GPKIDVVGYC FLDLSSNYEP PESLVKWLEA GDKPVYIGFG SLPVQDPEKM 240 TQIIIQALET TKQRGIINEG WGGLGKSAEP KDFLYLLDNC PHDWLFPKCK AVVHHGGAGT 300 TAAGLKAACP TTVVPFFGDQ PFWGERVHDK GVGPPPIPVD EFSLQRLVNA INYMLDPKVK 360 ERAVLLAKVL ENEDGVEGAV RAFFRQLSRR KLEPEPEPQK SNLLFIRKCF GCF* 420 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03033 | Glyco_transf_28 | 2.0e-16 | 27 | 116 | 113 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| COG1819 | COG1819 | 1.0e-24 | 29 | 386 | 386 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| cd03784 | GT1_Gtf_like | 1.0e-97 | 29 | 385 | 385 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI37267.1 | 0 | 27 | 412 | 197 | 614 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001052094.1 | 0 | 27 | 412 | 188 | 608 | Os04g0131900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002265023.1 | 0 | 27 | 412 | 244 | 661 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002321244.1 | 0 | 27 | 412 | 131 | 552 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002521125.1 | 0 | 27 | 412 | 206 | 625 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 2e-27 | 105 | 391 | 115 | 385 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 3h4i_A | 2e-27 | 105 | 391 | 115 | 385 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1iir_A | 1e-21 | 214 | 391 | 230 | 402 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 1rrv_B | 7e-17 | 192 | 370 | 207 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 7e-17 | 192 | 370 | 207 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX664063 | 295 | 69 | 363 | 0 |
| DV466557 | 287 | 89 | 375 | 0 |
| GT048365 | 316 | 102 | 412 | 0 |
| CX667156 | 276 | 69 | 344 | 0 |
| GT046352 | 317 | 27 | 311 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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