Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.084520.1 |
Family | GT47 |
Protein Properties | Length: 685 Molecular Weight: 77218.8 Isoelectric Point: 7.6598 |
Chromosome | Chromosome/Scaffold: 00862 Start: 239931 End: 243620 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 353 | 634 | 0 |
STLKVYIYREGARPIFHQGPLQSIYASEGWFMKILESNKKFVTKNPRKAHLFYLPFSSRQLEEVLYVRDSHSHKNLIQHLKNYLDFIAAKYPHWNRTGGA DHFLVACHDWAPAETRKYMAKCIRALCNSDVKEGFVFGKDVSLPETFVRVARNPLRDVGGNPSSKRPILAFFAGSMHGYLRSTLLEYWERKDPDMKISGP MPKVKGSKNYLWHMKNSKYCICAKGYEVNSPRVVESILYECVPVIISDNFVPPLFEVLNWESFAVFVAEKDIPNLKKILLSI |
Full Sequence |
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Protein Sequence Length: 685 Download |
MGQELFLISR IGTKKVLWLM GLMFAMILAF QCFELPYGFS LSSLLSAGKV SVIEEGSSQS 60 PVGEPKLKTE IVADSPLEEQ RENEFIPEQD HTLKESLELD IDDDGNNTSS SGDLMEPVDD 120 ATVDDESIDG VLQGNYQSFN GKDKSLRNDS MGTDGTESYV STLGYNNQSG HFATSPAVPP 180 TSSSSWIVRD TSNIAMNISR GNNYAASPAV PPISSSLLIV GNTSNNASNT SSHDVFVGPN 240 APDPSDKPDK SEKTKQSNSD SSTSKNKSVS KEKKVPKVPF SGVYTIADMN NLLFESRSNS 300 PLVPSWSSTA DQELLQAKLQ IENAPVIDND PNLYAPLFQN ISRFKRSYEL MESTLKVYIY 360 REGARPIFHQ GPLQSIYASE GWFMKILESN KKFVTKNPRK AHLFYLPFSS RQLEEVLYVR 420 DSHSHKNLIQ HLKNYLDFIA AKYPHWNRTG GADHFLVACH DWAPAETRKY MAKCIRALCN 480 SDVKEGFVFG KDVSLPETFV RVARNPLRDV GGNPSSKRPI LAFFAGSMHG YLRSTLLEYW 540 ERKDPDMKIS GPMPKVKGSK NYLWHMKNSK YCICAKGYEV NSPRVVESIL YECVPVIISD 600 NFVPPLFEVL NWESFAVFVA EKDIPNLKKI LLSIPEKRYR EMQMRVKKLQ PHFLWHAKPQ 660 KYDMFHMILH SIWYNRLYQI TPKL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-67 | 351 | 634 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 259 | 680 | 170 | 593 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_197954.1 | 0 | 1 | 681 | 1 | 653 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 680 | 1 | 666 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 228 | 683 | 16 | 471 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 289 | 683 | 1 | 398 | predicted protein [Populus trichocarpa] |