Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.090160.1 |
Family | GT47 |
Protein Properties | Length: 507 Molecular Weight: 57497.2 Isoelectric Point: 9.3358 |
Chromosome | Chromosome/Scaffold: 00894 Start: 1528496 End: 1533473 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 117 | 426 | 0 |
IRVYVYEMPWKFTYDLLWTFRNTYRETSNLTSNGSPVHRLIEQHSIDYWLWADLIAPESERLLKGVVRVYRQEEADLFYIPFFTTISFFLLEKQQCKALY REALKWVTDQPAWKRSEGRDHILPVHHPWSFKTVRKFMKNAIWLLPDMDSTGNWYKPGQVFLEKDLILPYVPNVELCDRKCLSYQQSKRSILLFFRGRLK RNAGGKIRAKLGGELSGADDVLIEEGTAGEGGKAAAQTGMRKSIFCLSPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGILDYRKIALFVSSSDALK SGWLLTYLRS |
Full Sequence |
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Protein Sequence Length: 507 Download |
MSAQIQRSNR SPLLLFTLSL LALSVLFILV FLSPSNPHPN TTSFHSPISS LKPETSFVVS 60 LEHFLTHKVP KSPPLRDDTA PVAGDVEDAS RKLDEALSEA EMERVIRDPY FPLGSPIRVY 120 VYEMPWKFTY DLLWTFRNTY RETSNLTSNG SPVHRLIEQH SIDYWLWADL IAPESERLLK 180 GVVRVYRQEE ADLFYIPFFT TISFFLLEKQ QCKALYREAL KWVTDQPAWK RSEGRDHILP 240 VHHPWSFKTV RKFMKNAIWL LPDMDSTGNW YKPGQVFLEK DLILPYVPNV ELCDRKCLSY 300 QQSKRSILLF FRGRLKRNAG GKIRAKLGGE LSGADDVLIE EGTAGEGGKA AAQTGMRKSI 360 FCLSPAGDTP SSARLFDAIV SGCIPVIVSD ELELPFEGIL DYRKIALFVS SSDALKSGWL 420 LTYLRSFSAA DIRRLQQNLA KLSRHFIYSS PAQPMGPEDL AWKMIGGKLV NIKLHTRRSQ 480 RVVKESRSVC SCDCRRSNFT NSPPSL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-63 | 115 | 427 | 321 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI20132.1 | 0 | 124 | 501 | 1 | 378 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197191.1 | 0 | 10 | 496 | 16 | 497 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002285599.1 | 0 | 50 | 501 | 59 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325382.1 | 0 | 35 | 500 | 43 | 501 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002520033.1 | 0 | 36 | 501 | 45 | 503 | catalytic, putative [Ricinus communis] |