Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.095760.1 |
Family | GT47 |
Protein Properties | Length: 412 Molecular Weight: 46842.2 Isoelectric Point: 7.259 |
Chromosome | Chromosome/Scaffold: 00919 Start: 1612645 End: 1615755 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 44 | 339 | 0 |
RLKVYVYDLPSKYNKKTLQKDPRCLTHMFAAEIYMHRFLLNSPVRTLNPDEADWFYTPIYVTCDLTPNGLPLPFKSPRMMRSAIQLISSNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIDRGILPLLQRATLVQTFGQRNHVCLNEGSITIPPYCPPQKMKTHLIPSETPRSIFVYFRGLFYDVNNDPEGGYYARGA RAAVWENFKNNPLFDISTDHPTTYYEDMQRAIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVDEKDVSNLDTILTSI |
Full Sequence |
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Protein Sequence Length: 412 Download |
MMKLWLWVFA IFLVSRIAAV PNAVPTERIS GSAGDVLEDN PVGRLKVYVY DLPSKYNKKT 60 LQKDPRCLTH MFAAEIYMHR FLLNSPVRTL NPDEADWFYT PIYVTCDLTP NGLPLPFKSP 120 RMMRSAIQLI SSNWPYWNRT EGADHFFVVP HDFGACFHYQ EEKAIDRGIL PLLQRATLVQ 180 TFGQRNHVCL NEGSITIPPY CPPQKMKTHL IPSETPRSIF VYFRGLFYDV NNDPEGGYYA 240 RGARAAVWEN FKNNPLFDIS TDHPTTYYED MQRAIFCLCP LGWAPWSPRL VEAVVFGCIP 300 VIIADDIVLP FADAIPWEEI GVFVDEKDVS NLDTILTSIP PDVILRKQRL LANPSMKRAM 360 MFPQPAQSGD AFHQILNGLA RKLPHDKGVY LKPGERILNW TAGPVGDLKP W* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-81 | 44 | 339 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33320.1 | 0 | 2 | 411 | 1 | 412 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | XP_002284685.1 | 0 | 2 | 411 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002297880.1 | 0 | 2 | 411 | 1 | 412 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002318180.1 | 0 | 2 | 411 | 1 | 417 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002511079.1 | 0 | 2 | 411 | 1 | 417 | catalytic, putative [Ricinus communis] |