y
Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.104410.1 |
Family | GT47 |
Protein Properties | Length: 465 Molecular Weight: 53549.6 Isoelectric Point: 9.5451 |
Chromosome | Chromosome/Scaffold: 00927 Start: 2941037 End: 2942431 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 76 | 414 | 0 |
PYVYVYDLPPEFNLGLLQDCRHLSVYTDMCPHVANRGLGRQVSTISTAANSWFATHQFIAEMIFHARMESHPCRTRNPNIADLFYIPFYGGLHASSKFRE PNITERDALAVRLVDYIQSQPTWWKNNGRDHFLALGRTAWDFMRNNANGPDFGANSLLTLNAVQNMSVLTVERNPWTGSNQFGIPYASYFHPYTSGEIKT WQNKMRQSNRSHLFTFIGAPRKGLEKAAIRNDIIQQCDMSSKCKLVNCRGEQGKECYDPGQVLRIMSESEFCLQAPGDSFTRRSTFDSILAGCIPVFFSP HTAYTQYFWYLPEKARDYSVYIDEKGEERKRIEEVLLKI |
Full Sequence |
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Protein Sequence Length: 465 Download |
MFSKKQSTIH IIPLIEREKN SKNKKPIIKP YILYNSLLLL SFILWFLIIF LCFPKSTLKN 60 SHNQTNNLVI TCDGPPYVYV YDLPPEFNLG LLQDCRHLSV YTDMCPHVAN RGLGRQVSTI 120 STAANSWFAT HQFIAEMIFH ARMESHPCRT RNPNIADLFY IPFYGGLHAS SKFREPNITE 180 RDALAVRLVD YIQSQPTWWK NNGRDHFLAL GRTAWDFMRN NANGPDFGAN SLLTLNAVQN 240 MSVLTVERNP WTGSNQFGIP YASYFHPYTS GEIKTWQNKM RQSNRSHLFT FIGAPRKGLE 300 KAAIRNDIIQ QCDMSSKCKL VNCRGEQGKE CYDPGQVLRI MSESEFCLQA PGDSFTRRST 360 FDSILAGCIP VFFSPHTAYT QYFWYLPEKA RDYSVYIDEK GEERKRIEEV LLKIPREKVK 420 KMREKIVKLI PKVTYKHPNS TDFQFKDAVD VALAALYKRV SSSVG 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-64 | 75 | 414 | 354 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42883.1 | 0 | 2 | 464 | 3 | 451 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_177014.1 | 0 | 2 | 464 | 3 | 451 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270383.1 | 0 | 78 | 464 | 125 | 503 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300452.1 | 0 | 72 | 459 | 1 | 394 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336132.1 | 0 | 69 | 459 | 19 | 415 | predicted protein [Populus trichocarpa] |