Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.129760.1 |
Family | GT47 |
Protein Properties | Length: 542 Molecular Weight: 63168 Isoelectric Point: 10.0652 |
Chromosome | Chromosome/Scaffold: 01028 Start: 554974 End: 560548 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 206 | 490 | 0 |
LKVYIYRDGSRPIFHTPHLRGIYASEGWFMKLMEENRQFVTKDPEKAHLFYLAYSSRQLQTALYVPDSHNMKPLSIYLRDHVNWIAGKYPYWNRTHGYDH FLVACHDWGPYTVNEHRELSQHTIKALCNADLSEGVFKLGKDVSLPETTIRTPRKPLRNVGGKRVSQRPILAFFAGNMHGRVRPILLKHWNDKDDDIRVY GPLPLRVSRKMTYIQHMKSSKYCICPMGYEVNSPRIIEAIYYECVPVIIADNFVLPFSEFLDWSAFSVVVAEKDIPKLKEILTAI |
Full Sequence |
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Protein Sequence Length: 542 Download |
MNKLLQRFSL YVMREVFRIS ISNKINWTKV CLIGAILTVG GIALQMLILP YPLHTWFVSR 60 PATVILYESM EETMELNETH KNSTERVPLI PLNSVVLQNA TDQMVQLVSV NQERETSPKK 120 RKSSRRRKHA KLKEKPIILT PPPPPRRPPS ALERHVWSLK PVEALAYAKE ELKHAPTVID 180 DADLYAPLFL NVSIFKRSYE LMELILKVYI YRDGSRPIFH TPHLRGIYAS EGWFMKLMEE 240 NRQFVTKDPE KAHLFYLAYS SRQLQTALYV PDSHNMKPLS IYLRDHVNWI AGKYPYWNRT 300 HGYDHFLVAC HDWGPYTVNE HRELSQHTIK ALCNADLSEG VFKLGKDVSL PETTIRTPRK 360 PLRNVGGKRV SQRPILAFFA GNMHGRVRPI LLKHWNDKDD DIRVYGPLPL RVSRKMTYIQ 420 HMKSSKYCIC PMGYEVNSPR IIEAIYYECV PVIIADNFVL PFSEFLDWSA FSVVVAEKDI 480 PKLKEILTAI PLKRYLTMQI NVKMVQKHFL WNPKPLKYDL FHMVLHSIWF SRLNLFPIPR 540 T* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-68 | 206 | 490 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 1 | 538 | 1 | 535 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 137 | 534 | 131 | 529 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 1 | 538 | 1 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303362.1 | 0 | 157 | 541 | 1 | 386 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530666.1 | 0 | 12 | 541 | 1 | 528 | catalytic, putative [Ricinus communis] |