Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.132400.1 |
Family | GT47 |
Protein Properties | Length: 395 Molecular Weight: 45638.8 Isoelectric Point: 9.7777 |
Chromosome | Chromosome/Scaffold: 01037 Start: 380250 End: 381882 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 60 | 345 | 0 |
KRFKVWSYREGEQPLFHDGPLNSIYAIEGQFIDELDCSKSPFRASHPDEAHVFLLPLSITNIIHFIYRPITSPADYNRDRMHRVTTDYIRVVANRYPYWN RSNGADHFVVSCHDWAPEISDANPQLFKNFIRVVCNANITEGFRPNIDIPLPEINIHPGTLGPPDLGQPPERRPILAFFAGGAHGYIRKILIKHWKEKDN EVQVHEYLPKTQNYTKLIGESKFCLCPSGYEVASPRVVEAIYGGCVPVIISDNYSLPFSDVLDWSRFSVQIPVQRIPEIKTILKAI |
Full Sequence |
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Protein Sequence Length: 395 Download |
KKKKTSLKMI EASLAEARAS IRKAVLWKNF TSEKKETYIP RGPIYRNPYA FHQSHIEMVK 60 RFKVWSYREG EQPLFHDGPL NSIYAIEGQF IDELDCSKSP FRASHPDEAH VFLLPLSITN 120 IIHFIYRPIT SPADYNRDRM HRVTTDYIRV VANRYPYWNR SNGADHFVVS CHDWAPEISD 180 ANPQLFKNFI RVVCNANITE GFRPNIDIPL PEINIHPGTL GPPDLGQPPE RRPILAFFAG 240 GAHGYIRKIL IKHWKEKDNE VQVHEYLPKT QNYTKLIGES KFCLCPSGYE VASPRVVEAI 300 YGGCVPVIIS DNYSLPFSDV LDWSRFSVQI PVQRIPEIKT ILKAISEEKY LKLYKGVIKV 360 KRHFKINRPA KPFDVIHMLL HSLWLRRLNF GLPH* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-71 | 58 | 345 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03872.1 | 0 | 1 | 392 | 73 | 465 | Exostosin-like [Medicago truncatula] |
GenBank | ABP03873.1 | 0 | 1 | 392 | 231 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 2 | 393 | 10 | 401 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 2 | 394 | 83 | 477 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 2 | 394 | 2 | 396 | PREDICTED: hypothetical protein [Vitis vinifera] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EC939466 | 294 | 2 | 293 | 0 |
JK524792 | 252 | 42 | 293 | 0 |
CO983212 | 231 | 163 | 392 | 0 |
FD507587 | 231 | 101 | 331 | 0 |
GO363500 | 279 | 89 | 366 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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