y
Basic Information | |
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Species | Cucumis sativus |
Cazyme ID | Cucsa.135930.1 |
Family | GT47 |
Protein Properties | Length: 476 Molecular Weight: 54423.6 Isoelectric Point: 6.7694 |
Chromosome | Chromosome/Scaffold: 01044 Start: 698425 End: 700097 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 55 | 397 | 0 |
CSGRYLFIQNIPSRFNSDLITNCQSLTRGTDKSDMCPYFVNSGLGPEIEDSRGVFLNNSWFKTNQFLLEVIFHNKMKQYECLTNDSAMASAVYVPFYAGL DISHYLWNPSITIRDSSARDFLSSISEKPEWKRMFGRDHFFVAGRISWDFRRQTDEVSDWGSKLRFLSESHNMTMLSVEASSWKNDFAIPYPTYFHPSKL SEIVEWQSLMRARQRQHLFTFTGAPRPDLTDSIRGMVIEQCRGSSLCKFIDCSSDGVNCDDPTTTMEAFQSSIFCLQPPGDSYTRRSIFDSILAGCIPVF FHPGTAYSQYLWHFPKNQTAYSVFIPVRNVKKWDESIEGILSG |
Full Sequence |
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Protein Sequence Length: 476 Download |
MEKRPFRTTC STDICFAIFI SSAIVWIFLW ISSSLNPNKL LLKPSPLSAR TLDPCSGRYL 60 FIQNIPSRFN SDLITNCQSL TRGTDKSDMC PYFVNSGLGP EIEDSRGVFL NNSWFKTNQF 120 LLEVIFHNKM KQYECLTNDS AMASAVYVPF YAGLDISHYL WNPSITIRDS SARDFLSSIS 180 EKPEWKRMFG RDHFFVAGRI SWDFRRQTDE VSDWGSKLRF LSESHNMTML SVEASSWKND 240 FAIPYPTYFH PSKLSEIVEW QSLMRARQRQ HLFTFTGAPR PDLTDSIRGM VIEQCRGSSL 300 CKFIDCSSDG VNCDDPTTTM EAFQSSIFCL QPPGDSYTRR SIFDSILAGC IPVFFHPGTA 360 YSQYLWHFPK NQTAYSVFIP VRNVKKWDES IEGILSGISK DRESSMREEV IRVIPSIVYG 420 DPRSKIGNLE DAFDLAVKGI LERVENVRKN IREGRDPSEG FDGPDHFKYT FSNND* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-54 | 98 | 398 | 315 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193135.2 | 0 | 44 | 472 | 89 | 512 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002280815.1 | 0 | 53 | 475 | 91 | 511 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300146.1 | 0 | 53 | 472 | 106 | 513 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002321098.1 | 0 | 38 | 472 | 30 | 466 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002532518.1 | 0 | 53 | 472 | 100 | 522 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |