| Basic Information | |
|---|---|
| Species | Cucumis sativus |
| Cazyme ID | Cucsa.147330.1 |
| Family | CBM57 |
| Protein Properties | Length: 608 Molecular Weight: 66644.8 Isoelectric Point: 6.5941 |
| Chromosome | Chromosome/Scaffold: 01106 Start: 17740 End: 39731 |
| Description | Di-glucose binding protein with Leucine-rich repeat domain |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| CBM57 | 193 | 339 | 3.5e-21 |
| NDTDVFGRSWQSDSIFIIPSLKQSVRVLSTAKSVSGADQQPNYFPMKLYQKAVTVGGTGVLEYELPVDAKLDYLVWLHFAEIDSSVKKAGQRVFDVVING NNATRIDIFAKVGSFAAYSWSYTMKNLSSSALSVKLVGVVGSPLLSG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 608 Download |
| MEIVNSISYH IDCGGLINST DPFGTTWLSD RFYTGGTTAI VSEPLIFRHP QEKNLRFFPL 60 SSGKKNCYII PNLPTGRYYF RTFTVYDNYD GKSHPPSFDA SIEGTLVFSW RSPWSEDLAR 120 HGAYSDLFAF IGDGEADFCF YSLSTDSPVI GSFQLVQVDP MSYNSTAIGE NFILVNYGRL 180 TCGSEQWGPG FSNDTDVFGR SWQSDSIFII PSLKQSVRVL STAKSVSGAD QQPNYFPMKL 240 YQKAVTVGGT GVLEYELPVD AKLDYLVWLH FAEIDSSVKK AGQRVFDVVI NGNNATRIDI 300 FAKVGSFAAY SWSYTMKNLS SSALSVKLVG VVGSPLLSGL ENYALVPRDL STAPEQVSAM 360 RALKESLRVP GRMGWNGDPC APTNWDAWEG ITCRPNKNAT ALVIFQIDLG SQGLKGYISD 420 QIVLLTNLVS LNLSSNSLGG TIPPGLGEHS LTRLDLSKNQ LTGSIPDSLA SRNLQLVILN 480 DNLLEGRVPE ELYSIGVHGG AIDLSSNKGL CGVPSLPTCP LFWEHGRLSK TGKIAIALSS 540 TFLFCALLAI IYICCIRRSR NDYDFGLPSE LLSLAAKRNR YQRQKSLMLL EMESQHAKGL 600 SPFTPLN* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam11721 | Malectin | 0.001 | 8 | 153 | 165 | + Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan. | ||
| PLN00113 | PLN00113 | 1.0e-6 | 442 | 492 | 53 | + leucine-rich repeat receptor-like protein kinase; Provisional | ||
| pfam11721 | Malectin | 2.0e-12 | 182 | 340 | 173 | + Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan. | ||
| pfam12819 | Malectin_like | 1.0e-55 | 11 | 343 | 352 | + Carbohydrate-binding protein of the ER. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. The domain is found on a number of plant receptor kinases. | ||
| PLN03150 | PLN03150 | 1.0e-114 | 11 | 541 | 541 | + hypothetical protein; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005515 | protein binding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAG50525.1 | 0 | 8 | 580 | 29 | 550 | AC084221_7 hypothetical protein [Arabidopsis thaliana] |
| RefSeq | NP_564237.2 | 0 | 8 | 607 | 29 | 626 | leucine-rich repeat protein-related [Arabidopsis thaliana] |
| RefSeq | XP_002281668.1 | 0 | 6 | 600 | 28 | 619 | PREDICTED: similar to leucine-rich repeat protein-related [Vitis vinifera] |
| RefSeq | XP_002457393.1 | 0 | 8 | 600 | 29 | 625 | hypothetical protein SORBIDRAFT_03g006620 [Sorghum bicolor] |
| RefSeq | XP_002524408.1 | 0 | 7 | 578 | 22 | 591 | serine-threonine protein kinase, plant-type, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4hq1_A | 0.000001 | 357 | 492 | 29 | 156 | A Chain A, Crystal Structure Of Barley Beta-D-Glucan Glucohydrolase Isoenzyme Exo1 In Complex With Gluco-Phenylimidazole |
| PDB | 3rgz_A | 0.000003 | 407 | 519 | 637 | 748 | A Chain A, Crystal Structure Of Barley Beta-D-Glucan Glucohydrolase Isoenzyme Exo1 In Complex With Gluco-Phenylimidazole |
| PDB | 3rgz_A | 0.0005 | 393 | 492 | 389 | 486 | A Chain A, Crystal Structure Of Barley Beta-D-Glucan Glucohydrolase Isoenzyme Exo1 In Complex With Gluco-Phenylimidazole |
| PDB | 3rgz_A | 0.0005 | 404 | 467 | 658 | 722 | A Chain A, Crystal Structure Of Barley Beta-D-Glucan Glucohydrolase Isoenzyme Exo1 In Complex With Gluco-Phenylimidazole |
