| Basic Information | |
|---|---|
| Species | Cucumis sativus |
| Cazyme ID | Cucsa.158900.1 |
| Family | GT2 |
| Protein Properties | Length: 669 Molecular Weight: 77061.6 Isoelectric Point: 9.0097 |
| Chromosome | Chromosome/Scaffold: 01142 Start: 941041 End: 943377 |
| Description | Cellulose-synthase-like C4 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT2 | 206 | 382 | 1.9e-28 |
| VQIPMCNEREVYAQSIAAACELDWPRNRILIQVLDDSDDGNLQRLIKEEVLSWNEKGVNIVYRHRLIRTGYKAGNLKSAMACDYVKDYEFVAILDADFQP NPDFLKLCIPHFKGNPELGLVQARWAFVNKEENLLTRLQNINLCFHFEVEQQVNGVFLNFFGFNGTAGVWRTKALEE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 669 Download |
| MAPSSVVVTI EKHNSFPLVE INGSESLLLP EKQKAASPKQ LTWVLLLKAH RALFFFSWLA 60 MTVKAVFASV KKRIAHAGLN ENDSKNRGKL YRFIKGFLVF SIVGLIFEVV AHFKKWNLGM 120 IQPLEAEVHG ILQWFYVSWL AFRIDYIAPL VLMLSKFCVV LFLIQSLDRL VLCFGCFWIK 180 YKKIKPMIQD DAYDLEDAST FPMVLVQIPM CNEREVYAQS IAAACELDWP RNRILIQVLD 240 DSDDGNLQRL IKEEVLSWNE KGVNIVYRHR LIRTGYKAGN LKSAMACDYV KDYEFVAILD 300 ADFQPNPDFL KLCIPHFKGN PELGLVQARW AFVNKEENLL TRLQNINLCF HFEVEQQVNG 360 VFLNFFGFNG TAGVWRTKAL EESGGWLERT TVEDMDIAVR AHLKGWKFIF LNDVKVLCEL 420 PESYEAYKKQ QHRWHSGPMQ LFRLCLPSII TSKISIWKKT NLIFLFFLLR KLILPFYSFT 480 LFCIILPLTM FIPEAELPLW VICYIPVFMS FLNILPSPKS FPFLIPYLLF ENTMSVTKFN 540 AMVSGLFQLG SSYEWVVTKK TGRSSESDFL ALAERESKTS NDEKILRRHS ESGLELLSKM 600 NQEEIKQKVA SKKKRNKVYR KELALAFLLL TASARSLLSE HGVHFYFLLF QGLSFLVVGL 660 DLIGEQMN* 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06435 | CESA_NdvC_like | 6.0e-30 | 206 | 443 | 239 | + NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. Bradyrhizobium japonicum synthesizes periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans during growth under hypoosmotic conditions. Two genes (ndvB, ndvC) are involved in the beta-(1, 3), beta-(1,6)-glucan synthesis. The ndvC mutant strain resulted in synthesis of altered cyclic beta-glucans composed almost entirely of beta-(1, 3)-glycosyl linkages. The periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans function for osmoregulation. The ndvC mutation also affects the ability of the bacteria to establish a successful symbiotic interaction with host plant. Thus, the beta-glucans may function as suppressors of a host defense response. | ||
| cd06423 | CESA_like | 2.0e-31 | 206 | 394 | 189 | + CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan. | ||
| COG1215 | COG1215 | 2.0e-33 | 142 | 444 | 306 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
| cd06421 | CESA_CelA_like | 3.0e-48 | 202 | 442 | 244 | + CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end. | ||
| cd06437 | CESA_CaSu_A2 | 1.0e-107 | 202 | 438 | 237 | + Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex. Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN82135.1 | 0 | 1 | 668 | 1 | 695 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI34964.1 | 0 | 1 | 667 | 1 | 628 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_566835.1 | 0 | 1 | 668 | 1 | 673 | ATCSLC04 (CELLULOSE-SYNTHASE LIKE C4); cellulose synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002280124.1 | 0 | 1 | 668 | 1 | 664 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002517383.1 | 0 | 1 | 668 | 1 | 662 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4hg6_A | 4e-22 | 201 | 510 | 139 | 457 | B Chain B, Structure Of A Cellulose Synthase - Cellulose Translocation Intermediate |
